Protective immune response against methicillin resistant Staphylococcus aureus in a murine model using a DNA vaccine approach
JPM Senna, DM Roth, JS Oliveira, DC Machado… - Vaccine, 2003 - Elsevier
Methicillin resistant Staphylococcus aureus (MRSA) are a major pathogen responsible for
serious hospital infections worldwide. These bacteria are resistant to all beta-lactam …
serious hospital infections worldwide. These bacteria are resistant to all beta-lactam …
Recombinant PBP2a as a vaccine candidate against methicillin-resistant Staphylococcus aureus: Immunogenicity and protectivity
S Haghighat, SD Siadat, SMR Sorkhabadi… - Microbial …, 2017 - Elsevier
Methicillin-resistant Staphylococcus aureus infections are focal and development of an
effective vaccine can help to control this infection. Here, recombinant PBP2a was studied in …
effective vaccine can help to control this infection. Here, recombinant PBP2a was studied in …
DNA vaccination by mecA sequence evokes an antibacterial immune response against methicillin-resistant Staphylococcus aureus
A Ohwada, M Sekiya, H Hanaki, KK Arai… - Journal of …, 1999 - academic.oup.com
More than 90% of methicillin-resistant Staphylococcus aureus (MRSA) isolates produce a
penicillin-binding protein PBP2′(or PBP2a) with low affinity forβ-lactam antibiotics. PBP2 …
penicillin-binding protein PBP2′(or PBP2a) with low affinity forβ-lactam antibiotics. PBP2 …
[PDF][PDF] Evaluation of the humoral immune response in BALB/c mice immunized with a naked DNA vaccine anti-methicillin-resistant Staphylococcus aureus
DM Roth, JP Senna, DC Machado - Genet Mol Res, 2006 - researchgate.net
Methicillin-resistant Staphylococcus aureus (MRSA) is the major pathogen involved in
nosocomial infections, leading to high rates of morbidity and mortality in hospitals …
nosocomial infections, leading to high rates of morbidity and mortality in hospitals …
[HTML][HTML] Cloning, expression and purification of penicillin binding protein2a (pbp2a) from methicillin resistant Staphylococcus aureus: A study on immunoreactivity in …
S Haghighat, SD Siadat, SMR Sorkhabadi… - Avicenna journal of …, 2013 - ncbi.nlm.nih.gov
Background Staphylococcus aureus (S. aureus) is a major nosocomial pathogen and the
infection with this organism in human is increasing due to the spread of antibiotic resistant …
infection with this organism in human is increasing due to the spread of antibiotic resistant …
[HTML][HTML] Monoclonal antibody anti-PBP2a protects mice against MRSA (methicillin-resistant Staphylococcus aureus) infections
FB Saraiva, ACC de Araújo, AÉV de Araújo… - PLoS …, 2019 - journals.plos.org
Methicillin-resistant Staphylococcus aureus (MRSA) is a multidrug-resistant bacterium
responsible for serious nosocomial and community-acquired infections worldwide. Since …
responsible for serious nosocomial and community-acquired infections worldwide. Since …
A novel recombinant vaccine candidate comprising PBP2a and autolysin against Methicillin Resistant Staphylococcus aureus confers protection in the experimental …
S Haghighat, SD Siadat, SMR Sorkhabadi… - Molecular …, 2017 - Elsevier
The methicillin-resistant Staphylococcus aureus infection is a hot topic area in microbiology
research. Here a novel vaccine candidate consisting of recombinant PBP2a and autolysin …
research. Here a novel vaccine candidate consisting of recombinant PBP2a and autolysin …
Passive immunization against methicillin resistant Staphylococcus aureus recombinant PBP2a in sepsis model of mice: comparable results with antibiotic therapy
RZ Naghshbandi, S Haghighat, M Mahdavi - International …, 2018 - Elsevier
Methicillin resistant Staphylococcus aureus (MRSA) is a representative pathogen that is
responsible for a nosocomial infection and considerable yearly mortality rate. Antibiotic …
responsible for a nosocomial infection and considerable yearly mortality rate. Antibiotic …
Development of an immunochromatographic strip for simple detection of penicillin-binding protein 2′
H Matsui, H Hanaki, M Inoue, H Akama… - Clinical and vaccine …, 2011 - Am Soc Microbiol
Infections with methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant
coagulase-negative Staphylococcus (MR-CNS) are a serious problem in hospitals because …
coagulase-negative Staphylococcus (MR-CNS) are a serious problem in hospitals because …
Penicillin‐binding protein PBP2a provides variable levels of protection toward different β‐lactams in Staphylococcus aureus RN4220
ME Fergestad, GA Stamsås… - …, 2020 - Wiley Online Library
Methicillin‐resistant Staphylococcus aureus (MRSA) is resistant to most β‐lactams due to
the expression of an extra penicillin‐binding protein, PBP2a, with low β‐lactam affinity. It has …
the expression of an extra penicillin‐binding protein, PBP2a, with low β‐lactam affinity. It has …
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