[HTML][HTML] Oxidative stress and mitochondrial dysfunction in early-onset and late-onset preeclampsia
R Marín, DI Chiarello, C Abad, D Rojas… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Preeclampsia is a pregnancy-specific syndrome with multisystem involvement which leads
to foetal, neonatal, and maternal morbidity and mortality. This syndrome is characterized by …
to foetal, neonatal, and maternal morbidity and mortality. This syndrome is characterized by …
The role of mitochondrial dysfunction in preeclampsia: causative factor or collateral damage?
AN Smith, X Wang, DG Thomas… - American journal of …, 2021 - academic.oup.com
Preeclampsia, new onset hypertension in pregnancy, affects~ 5%–10% of the world's
population. Preeclampsia is the leading cause of morbidity and mortality for both the mother …
population. Preeclampsia is the leading cause of morbidity and mortality for both the mother …
[HTML][HTML] Mitochondrial role in adaptive response to stress conditions in preeclampsia
PA Vishnyakova, MA Volodina, NV Tarasova… - Scientific reports, 2016 - nature.com
Preeclampsia (PE) is a pregnancy-specific syndrome, characterized in general by
hypertension with proteinuria or other systemic disturbances. PE is the major cause of …
hypertension with proteinuria or other systemic disturbances. PE is the major cause of …
[HTML][HTML] Placental mitochondrial function and dysfunction in preeclampsia
The placenta is a vital organ of pregnancy, regulating adaptation to pregnancy, gestational
parent/fetal exchange, and ultimately, fetal development and growth. Not surprisingly, in …
parent/fetal exchange, and ultimately, fetal development and growth. Not surprisingly, in …
[HTML][HTML] Placental mitochondrial adaptations in preeclampsia associated with progression to term delivery
Preeclampsia is a devastating pregnancy disorder. Severity varies widely, and while severe
preeclampsia often requires pre-term delivery, women with mild preeclampsia may reach …
preeclampsia often requires pre-term delivery, women with mild preeclampsia may reach …
[HTML][HTML] Placental mitochondrial abnormalities in preeclampsia
Abstract Preeclampsia complicates 5–8% of all pregnancies worldwide, and although its
pathophysiology remains obscure, placental oxidative stress and mitochondrial …
pathophysiology remains obscure, placental oxidative stress and mitochondrial …
Role of mitochondrial dysfunction and reactive oxygen species in mediating hypertension in the reduced uterine perfusion pressure rat model of preeclampsia
VR Vaka, KM McMaster, MW Cunningham Jr… - …, 2018 - Am Heart Assoc
Placental ischemia is believed to be the initial event in the development of preeclampsia.
Mitochondrial dysfunction is a cause of reactive oxygen species (ROS) generation and …
Mitochondrial dysfunction is a cause of reactive oxygen species (ROS) generation and …
Noncanonical mitochondrial unfolded protein response impairs placental oxidative phosphorylation in early-onset preeclampsia
HW Yung, F Colleoni, E Dommett… - Proceedings of the …, 2019 - National Acad Sciences
Preeclampsia (PE) is a dangerous complication of pregnancy, especially when it presents
at< 34 wk of gestation (PE< 34 wk). It is a major cause of maternal and fetal morbidity and …
at< 34 wk of gestation (PE< 34 wk). It is a major cause of maternal and fetal morbidity and …
[HTML][HTML] Therapeutically targeting mitochondrial redox signalling alleviates endothelial dysfunction in preeclampsia
C McCarthy, LC Kenny - Scientific reports, 2016 - nature.com
Aberrant placentation generating placental oxidative stress is proposed to play a critical role
in the pathophysiology of preeclampsia. Unfortunately, therapeutic trials of antioxidants have …
in the pathophysiology of preeclampsia. Unfortunately, therapeutic trials of antioxidants have …
Placental mitochondria and reactive oxygen species in the physiology and pathophysiology of pregnancy
Mitochondria are central to cell function. The placenta forms the interface between maternal
and fetal systems, and placental mitochondria have critical roles in maintaining pregnancy …
and fetal systems, and placental mitochondria have critical roles in maintaining pregnancy …