Osteoarthritis (OA) is the most common form of articular joint arthritis and a cause of
significant morbidity. In this review, we present the role of nerve growth factor (NGF) in pain …

Arthritis is characterized by pain and inflammation. Recently, attention has been focused on
nerve-growth factor (NGF), a neurotrophin that is a key regulator of peripheral nociception …

Objective Nerve growth factor (NGF) is a key regulator of nociceptive pain and thus appears
to be an interesting target molecule for an innovative class of analgesic medication. We set …

Nerve growth factor (NGF) is a neurotrophin that activates nociceptive neurons to transmit
pain signals from the peripheral to the central nervous system and that exerts its effects on …

National and international recommendations about the management of osteoarthritis
emphasize the need for combining pharmacological and non-pharmacological treatments …

Nerve growth factor (NGF) is a key regulator of chronic osteoarthritic pain, but the exact
targets of NGF action on human articular cartilage is unknown. This study aimed to test the …

Nerve growth factor (NGF) antagonism is on the verge of becoming a powerful analgesic
treatment for numerous conditions, including osteoarthritis and lower back pain. This review …

Background Inflammation is an essential component of arthritis pain. Nerve growth factor
(NGF) plays a key role in acute and chronic pain states especially those associated with …

Objectives Nerve growth factor (NGF) is a promising analgesic target, particularly in
osteoarthritis (OA) where existing therapies are inadequate. We hypothesised that pain …

There continues to be an unmet need for safe and effective pain medications. Opioids and
nonsteroidal anti-inflammatory drugs (NSAIDs) dominate the clinical landscape despite …