Programmed cell death has a vital role in embryonic development and tissue homeostasis.
Necroptosis is an alternative mode of regulated cell death mimicking features of apoptosis …

Necroptosis is a form of regulated cell death, which is induced by ligand binding to TNF
family death domain receptors, pattern recognizing receptors and virus sensors. The …

Cell death has a fundamental impact on the evolution of degenerative disorders,
autoimmune processes, inflammatory diseases, tumor formation and immune surveillance …

Neuroinflammation is a complex inflammatory process in the nervous system that is
expected to play a significant role in neurological diseases. Necroptosis is a kind of necrosis …

Necroptosis is a form of programmed necrosis that is mediated by various cytokines and
pattern recognition receptors (PRRs). Cells dying by necroptosis show necrotic phenotypes …

In the early 2000s, receptor-interacting serine/threonine protein kinase 1 (RIPK1), a
molecule already recognized as an important regulator of cell survival, inflammation and …

Necroptosis is a noncaspase-dependent and precisely regulated mechanism of cell death.
Necroptosis is mainly initiated by members of the tumor necrosis factor receptor (TNFR) and …

Over the past few decades, mechanisms of programmed cell death have attracted the
scientific community because they are involved in diverse human diseases. Initially …

Necroptosis, a form of regulated necrotic cell death, is mediated by receptor interacting
protein 1 (RIPK1), RIPK3, and mixed lineage kinase domain-like protein (MLKL). However …

Necroptosis, or regulated necrosis, is an important type of programmed cell death in addition
to apoptosis. Necroptosis induction leads to cell membrane disruption, inflammation and …