[Frontiers in Bioscience 13, 1857-1865, January 1, 2008] 1857 Crosstalk between G-protein-coupled
receptors and Epidermal growt Page 1 [Frontiers in Bioscience 13, 1857-1865, January 1 …

Epidermal growth factor receptor (EGFR), a receptor tyrosine kinase has four members in its
family. A set of specialized ligands have evolved which bind to and cause homodimerization …

Signaling via the epidermal growth factor (EGF)-receptor family is subject to regulation and
modulation by multiple ligands, effectors and negative regulators, as well as regulation by …

Both G protein-coupled receptors (GPCRs) and receptor-tyrosine kinases (RTKs) regulate
large signaling networks, control multiple cell functions and are implicated in many diseases …

Both the epidermal growth factor receptor (EGFR) and the insulin-like growth factor-1
receptor (IGF-1R) can contribute to tumor development and-progression through their effects …

The Epidermal growth factor receptor (EGFR) is a membrane spanning glycoprotein, which
frequently has been implicated in various cancer types. The mechanisms by which EGFR …

One prominent challenge facing cancer research is understanding the cellular processes
regulating cell growth and proliferation. A major advance in understanding the control of …

The epidermal growth factor receptor (EGFR) plays an important role in many types of
human cancers. Receptor amplification, autocrine activation and/or deletion of exons 2–7 of …

The epidermal growth factor receptor (EGFR) belongs to the ErbB family of receptor tyrosine
kinases (RTK). These trans-membrane proteins are activated following binding with peptide …

The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase receptor that is
frequently expressed in epithelial tumors. The EGFR was the first receptor to be proposed as …