The etiologic diagnosis of infectious discitis is improved by amplification‐based DNA analysis

F Lecouvet, L Irenge, B Vandercam… - … : Official Journal of …, 2004 - Wiley Online Library
Objective Blood cultures and cultures of disc material are required to identify and treat
bacterial agents responsible for septic spondylodiscitis, but these methods have limited …

Detection of bacterial DNA in joint samples from patients with undifferentiated arthritis and reactive arthritis, using polymerase chain reaction with universal 16S …

B Wilbrink, IM van der Heijden… - … : Official Journal of …, 1998 - Wiley Online Library
Objective Bacteria are considered to be important in the pathogenesis of several forms of
arthritis. The goal of this study was to apply the 16S ribosomal RNA (rRNA)‐polymerase …

Rapid diagnosis of septic arthritis using 16S rDNA PCR: a comparison of 3 methods

H Bonilla, R Kepley, J Pawlak, B Belian… - … and infectious disease, 2011 - Elsevier
Few studies address the utility of molecular techniques for diagnosis of infection in synovial
fluid (SF). We evaluated 3 different methods using 16S rDNA polymerase chain reaction …

Detection of bacterial DNA in serial synovial samples obtained during antibiotic treatment from patients with septic arthritis

IM Van Der Heijden, B Wilbrink… - … : Official Journal of …, 1999 - Wiley Online Library
Objective The management of septic arthritis could benefit from sensitive tests that detect the
persistence of microorganisms in the joint. The aim of this study was to determine the …

Identifying pathogens of spondylodiscitis: percutaneous endoscopy or CT-guided biopsy

SC Yang, TS Fu, LH Chen, WJ Chen, YK Tu - Clinical orthopaedics and …, 2008 - Springer
Identifying offending pathogens is crucial for appropriate antibiotic administration for
infectious spondylitis. Although computed tomography (CT)-guided biopsy for bacteriologic …

Microbiological and therapeutic challenges in infectious spondylodiscitis: a cohort study of 100 cases, 2006–2011

T Aagaard, C Roed, C Dragsted… - Scandinavian Journal of …, 2013 - Taylor & Francis
Background: The microbiological diagnosis of infectious spondylodiscitis is often difficult to
establish and the disease requires prolonged antibiotic treatment. We analyzed the medical …

[HTML][HTML] Pathogen identification in suspected cases of pyogenic spondylodiscitis

AF Sheikh, AD Khosravi, H Goodarzi… - Frontiers in Cellular …, 2017 - frontiersin.org
Pyogenic spinal infection continues to represent a worldwide problem. In approximately one-
third of patients with pyogenic spondylodiscitis, the infectious agent is never identified. Of the …

Bacterial DNA in synovial fluid cells of patients with juvenile onset spondyloarthropathies

C Pacheco‐Tena, C Alvarado De La Barrera… - …, 2001 - academic.oup.com
Objective. To identify bacterial DNA in synovial fluid cells of patients with active juvenile
onset spondyloarthropathy (SpA). Methods. The main group of study constituted 22 patients …

Chromosomal DNA from a variety of bacterial species is present in synovial tissue from patients with various forms of arthritis

HC Gérard, Z Wang, GF Wang… - … : Official Journal of …, 2001 - Wiley Online Library
Objective We and others have reported the presence of Chlamydia and other bacterial
species in joint specimens from patients with reactive arthritis (ReA). The present study was …

A case ascertainment study of septic discitis: clinical, microbiological and radiological features

N Hopkinson, J Stevenson, S Benjamin - Qjm, 2001 - academic.oup.com
We studied the spectrum of septic discitis presenting to two busy district general hospitals
over 2.5 years (November 1996 to April 1999), surveying the case notes of all patients …