Exosome-transmitted lncRNA UFC1 promotes non-small-cell lung cancer progression by EZH2-mediated epigenetic silencing of PTEN expression

X Zang, J Gu, J Zhang, H Shi, S Hou, X Xu… - Cell death & …, 2020 - nature.com
Abstract Long non-coding RNAs (LncRNAs) have been suggested as important regulators of
cancer development and progression in non-small cell lung cancer (NSCLC). Nevertheless …

[HTML][HTML] lncRNA UCA1 promotes gefitinib resistance as a ceRNA to target FOSL2 by sponging miR-143 in non-small cell lung cancer

X Chen, Z Wang, F Tong, X Dong, G Wu… - … Therapy-Nucleic Acids, 2020 - cell.com
Exosomes could mediate cell-cell crosstalk in cancer progression by transferring long
noncoding RNAs (lncRNAs). The aim of this study is to explore the roles of the exosomal …

[HTML][HTML] Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis

X Lv, Y Lian, Z Liu, J Xiao, D Zhang, X Yin - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Non-small cell lung cancer (NSCLC) is the most common tumor affecting modern people
and is associated with severe morbidity and high mortality. Exosomal long non-coding RNAs …

Exosomal lncRNA FOXD3-AS1 upregulates ELAVL1 expression and activates PI3K/Akt pathway to enhance lung cancer cell proliferation, invasion, and 5-fluorouracil …

G Mao, Z Mu, DA Wu - Acta biochimica et biophysica Sinica, 2021 - academic.oup.com
Long non-coding RNA (lncRNA) FOXD3-AS1 expression is upregulated in lung cancer;
however, its effect and mechanism on 5-fluorouracil (5-FU) resistance remain unclear. In this …

[HTML][HTML] Long non-coding RNAs and exosomal lncRNAs: Potential functions in lung cancer progression, drug resistance and tumor microenvironment remodeling

M Entezari, M Ghanbarirad, A Taheriazam… - Biomedicine & …, 2022 - Elsevier
Among the different kinds of tumors threatening human life, lung cancer is one that is
commonly observed in both males and females. The aggressive behavior of lung cancer …

[HTML][HTML] Exosome-transmitted long non-coding RNA SENP3-EIF4A1 suppresses the progression of hepatocellular carcinoma

J Wang, J Pu, Y Zhang, T Yao, Z Luo, W Li, G Xu… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Extracellular communication mediated by exosomes in a tumor microenvironment can
substantially affect tumor progression. However, the effect of exosomal long non-coding …

LncRNA-UCA1 exerts oncogenic functions in non-small cell lung cancer by targeting miR-193a-3p

W Nie, H Ge, X Yang, X Sun, H Huang, X Tao, W Chen… - Cancer letters, 2016 - Elsevier
Recently, the long non-coding RNA (lncRNA) urothelial carcinoma-associated 1 (UCA1) has
been identified as an oncogenic gene in multiple human tumor entitles, and dysregulation of …

Exosomal LncRNA RP5-977B1 as a novel minimally invasive biomarker for diagnosis and prognosis in non-small cell lung cancer

L Min, T Zhu, B Lv, T An, Q Zhang, Y Shang… - International journal of …, 2022 - Springer
Background Lung cancer is the leading cause of cancer-related deaths in the world. Non-
small cell lung cancer (NSCLC) accounts for 85% of all lung cancer cases. For lack of …

Exosomal long noncoding RNA MLETA1 promotes tumor progression and metastasis by regulating the miR-186-5p/EGFR and miR-497-5p/IGF1R axes in non-small …

XR Hsu, JE Wu, YY Wu, SY Hsiao, JL Liang… - Journal of Experimental …, 2023 - Springer
Background Lung cancer is the most common and deadliest cancer worldwide, and
approximately 90% of all lung cancer deaths are caused by tumor metastasis. Tumor …

Tumor-secreted exosomal lncRNA POU3F3 promotes cisplatin resistance in ESCC by inducing fibroblast differentiation into CAFs

Y Tong, L Yang, C Yu, W Zhu, X Zhou, Y Xiong… - Molecular Therapy …, 2020 - cell.com
Cancer-associated fibroblasts (CAFs), an activated subpopulation of fibroblasts, occupy a
central position in the tumor microenvironment and have been shown to promote …