Interplay between inflammation and thrombosis in cardiovascular pathology

K Stark, S Massberg - Nature Reviews Cardiology, 2021 - nature.com
Thrombosis is the most feared complication of cardiovascular diseases and a main cause of
death worldwide, making it a major health-care challenge. Platelets and the coagulation …

Inflammation and thrombosis in cardiovascular disease

P Nagareddy, SS Smyth - Current opinion in hematology, 2013 - journals.lww.com
Inflammation and thrombosis in cardiovascular disease : Current Opinion in Hematology
Inflammation and thrombosis in cardiovascular disease : Current Opinion in Hematology Log …

A link between inflammation and thrombosis in atherosclerotic cardiovascular diseases: Clinical and therapeutic implications

E Oikonomou, M Leopoulou, P Theofilis… - Atherosclerosis, 2020 - Elsevier
The association between thrombosis and acute coronary syndromes is well established.
Inflammation and activation of innate and adaptive immunity are another important factor …

Thrombosis as an intravascular effector of innate immunity

B Engelmann, S Massberg - Nature Reviews Immunology, 2013 - nature.com
Thrombosis is the most frequent cause of mortality worldwide and is closely linked to
haemostasis, which is the biological mechanism that stops bleeding after the injury of blood …

Thrombo-inflammation in cardiovascular disease: an expert consensus document from the Third Maastricht Consensus Conference on Thrombosis

E d'Alessandro, C Becker, W Bergmeier… - Thrombosis and …, 2020 - thieme-connect.com
Thrombo-inflammation describes the complex interplay between blood coagulation and
inflammation that plays a critical role in cardiovascular diseases. The third Maastricht …

A targetable pathway in neutrophils mitigates both arterial and venous thrombosis

L Nayak, DR Sweet, A Thomas, SD Lapping… - Science translational …, 2022 - science.org
Arterial and venous thrombosis constitutes a major source of morbidity and mortality
worldwide. Long considered as distinct entities, accumulating evidence indicates that …

Inflammation and cardiovascular diseases: lessons from seminal clinical trials

L Liberale, F Montecucco, L Schwarz… - Cardiovascular …, 2021 - academic.oup.com
Inflammation has been long regarded as a key contributor to atherosclerosis. Inflammatory
cells and soluble mediators play critical roles throughout arterial plaque development and …

Blood coagulation in immunothrombosis—at the frontline of intravascular immunity

F Gaertner, S Massberg - Seminars in immunology, 2016 - Elsevier
While hemostasis is the physiological process that prevents blood loss after vessel injury,
thrombosis is often portrayed as a pathologic event involving blood coagulation and platelet …

[HTML][HTML] Inflammation and cardiovascular disease: the future

N Arnold, K Lechner, C Waldeyer… - European Cardiology …, 2021 - ncbi.nlm.nih.gov
Despite considerable advances in reducing the global burden of atherosclerotic
cardiovascular disease by targeting conventional risk factors, significant residual risk …

Inflammatory processes in cardiovascular disease: a route to targeted therapies

N Ruparelia, JT Chai, EA Fisher… - Nature reviews …, 2017 - nature.com
Inflammatory processes are firmly established as central to the development and
complications of cardiovascular diseases. Elevated levels of inflammatory markers have …