[HTML][HTML] New insights into the role of mitochondrial metabolic dysregulation and immune infiltration in septic cardiomyopathy by integrated bioinformatics analysis and …

Y Li, J Yu, R Li, H Zhou, X Chang - Cellular & Molecular Biology Letters, 2024 - Springer
Background Septic cardiomyopathy (SCM), a common cardiovascular comorbidity of sepsis,
has emerged among the leading causes of death in patients with sepsis. SCM's …

[HTML][HTML] Exploring potential therapeutic agents for lipopolysaccharide-induced septic cardiomyopathy based on transcriptomics using bioinformatics

S Feng, K Cai, S Lin, X Chen, Y Luo, J Wang, G Lian… - Scientific Reports, 2023 - nature.com
Septic cardiomyopathy (SCM) is a common and severe complication of sepsis,
characterized by left ventricular dilation and reduced ejection fraction leading to heart …

[HTML][HTML] Identification and validation of immune-related biomarker gene and construction of ceRNA networks in septic cardiomyopathy

J Li, X Wu, C Li, G Sun, P Ding, Y Li, P Yang… - Frontiers in Cellular …, 2022 - frontiersin.org
Septic cardiomyopathy (SCM) is a cardiac dysfunction caused by severe sepsis, which
greatly increases the risk of heart failure and death, and its molecular mechanism is unclear …

[HTML][HTML] Identification of novel biomarkers in septic cardiomyopathy via integrated bioinformatics analysis and experimental validation

F Lu, F Hu, B Qiu, H Zou, J Xu - Frontiers in Genetics, 2022 - frontiersin.org
Purpose: Septic cardiomyopathy (SCM) is an important world public health problem with
high morbidity and mortality. It is necessary to identify SCM biomarkers at the genetic level to …

Identification of biomarkers associated with septic cardiomyopathy based on bioinformatics analyses

M Chen, C Kong, Z Zheng, Y Li - Journal of Computational Biology, 2020 - liebertpub.com
This study intended to identify biomarkers for septic cardiomyopathy (SC). Microarray data
GSE79962 including 20 SC samples and 11 normal samples were downloaded from the …

[HTML][HTML] Identification and validation of a novel mitochondrion-related gene signature for diagnosis and immune infiltration in sepsis

S Hao, M Huang, X Xu, X Wang, Y Song… - Frontiers in …, 2023 - frontiersin.org
Background Owing to the complex pathophysiological features and heterogeneity of sepsis,
current diagnostic methods are not sufficiently precise or timely, causing a delay in …

[HTML][HTML] Dysregulated autophagy-related genes in septic cardiomyopathy: comprehensive bioinformatics analysis based on the human transcriptomes and …

HX Zou, BQ Qiu, ZY Zhang, T Hu, L Wan… - Frontiers in …, 2022 - frontiersin.org
Septic cardiomyopathy (SCM) is severe organ dysfunction caused by sepsis that is
associated with poor prognosis, and its pathobiological mechanisms remain unclear …

Potentially Critical Roles of NDUFB5, TIMMDC1, and VDAC3 in the Progression of Septic Cardiomyopathy Through Integrated Bioinformatics Analysis

K Kang, J Li, R Li, X Xu, J Liu, L Qin, T Huang… - DNA and cell …, 2020 - liebertpub.com
Septic cardiomyopathy (SC) is a rare and harmful cardiovascular disease with decreased
left ventricular (LV) output and multiple organ failure, which poses a serious threat to human …

[HTML][HTML] Role of mitochondrial metabolic disorder and immune infiltration in diabetic cardiomyopathy: new insights from bioinformatics analysis

C Peng, Y Zhang, X Lang, Y Zhang - Journal of translational medicine, 2023 - Springer
Background Diabetic cardiomyopathy (DCM) is one of the common cardiovascular
complications of diabetes and a leading cause of death in diabetic patients. Mitochondrial …

Identification of biomarkers and pathways of mitochondria in sepsis patients

G Yuan - bioRxiv, 2021 - biorxiv.org
Sepsis is a life-threatening condition associate with significant morbidity and mortality, but
limited treatment. Mitochondria are recently recognized to be related to the pathophysiology …