Automated immunoassays used to evaluate thyroid function are vulnerable to different types
of interference that can affect clinical decisions. This review provides a detailed overview of …

This chapter reviews how improvements in sensitivity and specificity of thyroid function tests
[total and free thyroid hormones, TSH, thyroid autoantibodies (TRAb, TPOAb and TgAb) and …

Immunoassays are now commonly used for hormone measurement, in high throughput
analytical platforms. Immunoassays are generally robust to interference. However …

Measurements of thyrotropin and of total and free thyroxine and triiodothyronine are widely
used diagnostic methods for thyroid function evaluation. However, some serum samples will …

Clinically relevant interassay precision profiles for thyrotropin (thyroid-stimulating hormone;
TSH) were constructed with human serum pools measured over 4-8 weeks by six …

Background: Laboratory testing of serum thyroid-stimulating hormone (TSH) is an essential
tool for the diagnosis and management of various thyroid disorders whose collective …

Background: Immunoassays are used in almost all medical and surgical specialties, but they
suffer from interference from proteins such as antibodies in some patients' sera. Such …

Current medical needs dictate that laboratories offer thyrotropin (TSH) assays that can
reliably measure low TSH concentrations--a prerequisite for using the more cost-effective …

Since its introduction five years ago, the sensitive TSH (S-TSH) immunometric assay (IMA)
has established itself as an important new thyroid test. In fact, TSH IMAs have now replaced …

Serum thyroglobulin (Tg) measurement is a major means of detecting thyroid cancer
recurrence. Unlike anti-Tg autoantibody interferences, heterophile antibody (HAB) …