Synthesis and in vitro antitumor activity of new substituted thiopyrimidine acyclic nucleosides and their thioglycoside analogs

WA El-Sayed, AE Rashad, SM Awad… - … , Nucleotides and Nucleic …, 2009 - Taylor & Francis
Some new thiopyrimidine acyclic nucleosides and thioglycoside derivatives 3a-c, 4a-c, 6a,
b, and 7a, b were synthesized. The cytotoxicity and antitumor evaluation of all prepared …

Synthesis and In Vivo antitumor and antiviral activities of 2′‐deoxyribofuranosyl and arabinofuranosyl nucleosides of certain purine‐6‐sulfenamides, sulfinamides …

GR Revankar, NB Hanna, K Ramasamy… - Journal of …, 1990 - Wiley Online Library
Deoxyribofuranosyl and arabinofuranosyl nucleosides of certain purine‐6‐sulfenamides,
sulfinamides and sulfonamides have been prepared by sequential amination and controlled …

Synthetic nucleosides and nucleotides. X. Synthesis and biological activities of several purin-6-yl benzyl disulfides and their ribonucleosides

M Saneyoshi, M Inomata, T Sekine, A Hoshi… - Journal of …, 1978 - jstage.jst.go.jp
抄録 Reaction of S-benzylthioisothiouronium hydrochloride with 6-mercaptopurine (1), 9-β-D-
ribofuranosyl-6-mercaptopurine (2), 6-thioguanine (3) and 9-β-D-ribofuranosyl-6 …

Novel nucleoside analogues: first synthesis of pyridine-4-thioglycosides and their cytotoxic evaluation

G Elgemeie, M Abou-Zeid, S Alsaid… - … and Nucleic Acids, 2015 - Taylor & Francis
The reaction of sodium 2, 2-dicyanoethene-1, 1-bis (thiolate) with 2-cyano-N-arylacetamides
afforded sodium pyridine-4-thiolates, coupling of the latters with 2, 3, 4, 6-tetra-O-acetyl-D …

Syntheses and antitumor activities of D-and L-2′-deoxy-4′-thio pyrimidine nucleosides

J Uenishi, K Takahashi, M Motoyama… - … Nucleotides & Nucleic …, 1994 - Taylor & Francis
Abstract Both enantiomers of 2′-deoxy-4′-thiouridine (9) and 15, 4′-thiothymidine (10)
and 16, and 2′-deoxy-4′-thiocytidine (14) and 17 and 1-(2-deoxy-4-thio-β-D-erythro …

Anticancer activity of new substituted pyrimidines, their thioglycosides and thiazolopyrimidine derivatives

MNM Yousif, WA El-Sayed, HAS Abbas… - Journal of applied …, 2017 - japsonline.com
Novel functionalized pyrimidine, thioxopyrimidine, iminopyrimidine derivatives and their
derived bicyclic thiazolopyrimidine compounds were synthesized. The substituted arylidine …

The synthesis and biological activity of certain 4′-thionucleosides

JA Secrist III, WB Parker, KN Tiwari… - … Nucleotides & Nucleic …, 1995 - Taylor & Francis
The Synthesis and Biological Activity of Certain 4′-Thionucleosides Page 1 NUCLEOSIDES
& NUCLEOTIDES, 14(3-5), 675-686 (1 995) THE SYNTHESIS AND BIOLOGICAL ACTIVITY …

A new class of antimetabolites: pyridine thioglycosides as potential anticancer agents

GH Elgemeie, EM Mahdy, MA Elgawish… - … für Naturforschung C, 2010 - degruyter.com
The present study was designed for highlighting and focusing on the cytotoxic activity of a
new class of antimetabolites both on human cell lines, namely liver carcinoma cell line …

Nucleosides 79: Synthesis, Structure, and Biological Activity of New 6-Arylidenamino-2-Thio- and 2-Benzylthiopyrimidine N-Nucleosides

MAN Mosselhi, LM Break - Nucleosides, Nucleotides and Nucleic …, 2011 - Taylor & Francis
The condensation of 6-amino-2-thioxo-2, 3-dihydro-1H-pyrimidine-4-one [compound (1)]
with aromatic aldehydes (2) afforded azomethine derivatives (3). The formed azomethines …

Synthetic studies on 2′-substituted-4′-thiocytidine derivatives as antineoplastic agents

Y Yoshimura, M Endo, K Kitano, K Yamada… - … Nucleotides & Nucleic …, 1999 - Taylor & Francis
Synthetic Studies on 2′-Substituted-4′-thiocytidine Derivatives as Antineoplastic Agents
Page 1 NUCLEOSIDES & NUCLEOTIDES, 18(4&5), 8 15-820 (1 999) SYNTHETIC STUDIES …