Network control principles predict neuron function in the Caenorhabditis elegans connectome

G Yan, PE Vértes, EK Towlson, YL Chew, DS Walker… - Nature, 2017 - nature.com
Recent studies on the controllability of complex systems offer a powerful mathematical
framework to systematically explore the structure–function relationship in biological, social …

Connectomes across development reveal principles of brain maturation

D Witvliet, B Mulcahy, JK Mitchell, Y Meirovitch… - Nature, 2021 - nature.com
An animal's nervous system changes as its body grows from birth to adulthood and its
behaviours mature,,,,,,–. The form and extent of circuit remodelling across the connectome is …

[HTML][HTML] Neural signal propagation atlas of Caenorhabditis elegans

F Randi, AK Sharma, S Dvali, AM Leifer - Nature, 2023 - nature.com
Establishing how neural function emerges from network properties is a fundamental problem
in neuroscience. Here, to better understand the relationship between the structure and the …

Whole-animal connectomes of both Caenorhabditis elegans sexes

SJ Cook, TA Jarrell, CA Brittin, Y Wang, AE Bloniarz… - Nature, 2019 - nature.com
Abstract Knowledge of connectivity in the nervous system is essential to understanding its
function. Here we describe connectomes for both adult sexes of the nematode …

Spatiotemporal control of a novel synaptic organizer molecule

K Howell, JG White, O Hobert - Nature, 2015 - nature.com
Synapse formation is a process tightly controlled in space and time. How gene regulatory
mechanisms specify spatial and temporal aspects of synapse formation is not well …

A mesoscale connectome of the mouse brain

SW Oh, JA Harris, L Ng, B Winslow, N Cain, S Mihalas… - Nature, 2014 - nature.com
Comprehensive knowledge of the brain's wiring diagram is fundamental for understanding
how the nervous system processes information at both local and global scales. However …

[HTML][HTML] Neuronal contact predicts connectivity in the C. elegans brain

SJ Cook, CA Kalinski, O Hobert - Current Biology, 2023 - cell.com
Axons must project to particular brain regions, contact adjacent neurons, and choose
appropriate synaptic targets to form a nervous system. Multiple mechanisms have been …

A multi-scale brain map derived from whole-brain volumetric reconstructions

CA Brittin, SJ Cook, DH Hall, SW Emmons, N Cohen - Nature, 2021 - nature.com
Animal nervous system organization is crucial for all body functions and its disruption can
lead to severe cognitive and behavioural impairment. This organization relies on features …

Controllability of complex networks

YY Liu, JJ Slotine, AL Barabási - nature, 2011 - nature.com
The ultimate proof of our understanding of natural or technological systems is reflected in
our ability to control them. Although control theory offers mathematical tools for steering …

Role of graph architecture in controlling dynamical networks with applications to neural systems

JZ Kim, JM Soffer, AE Kahn, JM Vettel, F Pasqualetti… - Nature physics, 2018 - nature.com
Networked systems display complex patterns of interactions between components. In
physical networks, these interactions often occur along structural connections that link …