Targeting cell death: pyroptosis, ferroptosis, apoptosis and necroptosis in osteoarthritis
J Yang, S Hu, Y Bian, J Yao, D Wang, X Liu… - Frontiers in cell and …, 2022 - frontiersin.org
New research has shown that the development of osteoarthritis (OA) is regulated by different
mechanisms of cell death and types of cytokines. Therefore, elucidating the mechanism of …
mechanisms of cell death and types of cytokines. Therefore, elucidating the mechanism of …
Current understanding of osteoarthritis pathogenesis and relevant new approaches
Osteoarthritis (OA) is the most common degenerative joint disease that causes painful
swelling and permanent damage to the joints in the body. The molecular mechanisms of OA …
swelling and permanent damage to the joints in the body. The molecular mechanisms of OA …
The role of apoptosis in the pathogenesis of osteoarthritis
SQ Xiao, M Cheng, L Wang, J Cao, L Fang… - International …, 2023 - Springer
Purpose Apoptosis is an important physiological process, making a great difference to
development and tissue homeostasis. Osteoarthritis (OA) is a chronic joint disease …
development and tissue homeostasis. Osteoarthritis (OA) is a chronic joint disease …
Crosstalk between ferroptosis and chondrocytes in osteoarthritis: a systematic review of in vivo and in vitro studies
Purpose Recent scientific reports have revealed a close association between ferroptosis
and the occurrence and development of osteoarthritis (OA). Nevertheless, the precise …
and the occurrence and development of osteoarthritis (OA). Nevertheless, the precise …
[HTML][HTML] Chondrocyte ferroptosis contribute to the progression of osteoarthritis
X Yao, K Sun, S Yu, J Luo, J Guo, J Lin, G Wang… - Journal of orthopaedic …, 2021 - Elsevier
Background Osteoarthritis (OA) is a complex process comprised of mechanical load,
inflammation, and metabolic factors. It is still unknown that if chondrocytes undergo …
inflammation, and metabolic factors. It is still unknown that if chondrocytes undergo …
[HTML][HTML] Pyroptosis plays a role in osteoarthritis
S An, H Hu, Y Li, Y Hu - Aging and disease, 2020 - ncbi.nlm.nih.gov
Recent studies have revealed novel forms of cell death beyond the canonical types of
cellular apoptosis and necrosis, and these novel forms of cell death are induced by extreme …
cellular apoptosis and necrosis, and these novel forms of cell death are induced by extreme …
Insights on molecular mechanisms of chondrocytes death in osteoarthritis
E Charlier, B Relic, C Deroyer, O Malaise… - International journal of …, 2016 - mdpi.com
Osteoarthritis (OA) is a joint pathology characterized by progressive cartilage degradation.
Medical care is mainly based on alleviating pain symptoms. Compelling studies report the …
Medical care is mainly based on alleviating pain symptoms. Compelling studies report the …
The role played by ferroptosis in osteoarthritis: evidence based on iron dyshomeostasis and lipid peroxidation
S Zhang, J Xu, H Si, Y Wu, S Zhou, B Shen - Antioxidants, 2022 - mdpi.com
Ferroptosis, a recently discovered regulated cell death modality, is characterised by iron-
dependent accumulation of lipid hydroperoxides, which can reach lethal levels but can be …
dependent accumulation of lipid hydroperoxides, which can reach lethal levels but can be …
Ferroptosis Plays a Role in Human Chondrocyte of Osteoarthritis Induced by IL-1β In Vitro
W Xu, B Zhang, C Xi, Y Qin, X Lin, B Wang… - Cartilage, 2023 - journals.sagepub.com
Objective Osteoarthritis (OA) is a common disease with complex and unclear pathogenesis.
Ferroptosis is a new cell death mode, which is proved to be involved in different kinds of …
Ferroptosis is a new cell death mode, which is proved to be involved in different kinds of …
The regulatory role and therapeutic application of pyroptosis in musculoskeletal diseases
S Wang, H Wang, C Feng, C Li, Z Li, J He, C Tu - Cell Death Discovery, 2022 - nature.com
Pyroptosis is a controlled form of inflammatory cell death characterized by inflammasome
activation, pore formation, and cell lysis. According to different caspases, pyroptosis can be …
activation, pore formation, and cell lysis. According to different caspases, pyroptosis can be …