Efficacy of fifth generation cephalosporins against methicillin-resistant Staphylococcus aureus-A review

SR Selvan, D Ganapathy - Research Journal of Pharmacy and …, 2016 - indianjournals.com
In recent decades, microbial resistance has reached to an incredibly alarming levels,
leading to the development of more potent antimicrobial agents. MRSA (Methicillin-Resistant …

In Vitro Activity of Ceftaroline Against Multidrug-Resistant Staphylococcus aureus and Streptococcus pneumoniae: A Review of Published Studies and the AWARE …

DJ Farrell, M Castanheira, RE Mendes… - Clinical infectious …, 2012 - academic.oup.com
Ceftaroline is a new broad-spectrum parenteral cephalosporin with antibacterial activity
against the prevalent pathogens causing both acute bacterial skin and skin structure …

Ceftaroline fosamil: a novel broad-spectrum cephalosporin with expanded anti-Gram-positive activity

D Biek, IA Critchley, TA Riccobene… - Journal of antimicrobial …, 2010 - academic.oup.com
Ceftaroline fosamil is a novel cephalosporin with broad-spectrum activity against Gram-
positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA) and …

Off-label use of ceftaroline fosamil: a systematic review

A Pani, F Colombo, F Agnelli, V Frantellizzi… - International journal of …, 2019 - Elsevier
Ceftaroline fosamil is a fifth-generation cephalosporin with anti-methicillin-resistant
Staphylococcus aureus (MRSA) activity. It has been approved by the EMA and FDA for the …

Ceftaroline: A Novel Broad-Spectrum Cephalosporin with Activity against Meticillin-Resistant Staphylococcus aureus

GG Zhanel, G Sniezek, F Schweizer, S Zelenitsky… - Drugs, 2009 - Springer
Ceftaroline is a broad-spectrum cephalosporin currently under clinical investigation for the
treatment of complicated skin and skin-structure infections (cSSSI), including those caused …

Ceftaroline: A Novel Cephalosporin with Activity against Methicillin-resistant Staphylococcus aureus

LD Saravolatz, GE Stein… - Clinical infectious …, 2011 - academic.oup.com
Abstract Ceftaroline (PPI 0903, formerly TAK-599), the active metabolite of a N-phosphono
prodrug, ceftaroline fosamil, has been approved by the US Food and Drug Administration for …

Ceftaroline activity against pathogens associated with complicated skin and skin structure infections: results from an international surveillance study

RN Jones, RE Mendes, HS Sader - Journal of antimicrobial …, 2010 - academic.oup.com
Objectives To assess the spectrum and potency of ceftaroline, a novel anti-methicillin-
resistant staphylococcal cephalosporin, against a 2008 surveillance collection of clinical …

Ceftaroline for Severe Methicillin-Resistant Staphylococcus aureus Infections: A Systematic Review

RA Cosimi, N Beik, DW Kubiak… - Open forum infectious …, 2017 - academic.oup.com
Ceftaroline is approved by the Food and Drug Administration for acute bacterial skin and
skin-structure infections and community-acquired bacterial pneumonia, including cases with …

Methicillin-resistant Staphylococcus aureus bacteraemia and endocarditis treated with ceftaroline salvage therapy

TT Ho, J Cadena, LM Childs… - Journal of …, 2012 - academic.oup.com
Background One of the newest methicillin-resistant Staphylococcus aureus (MRSA)
antibiotics to receive FDA approval is ceftaroline fosamil, a member of a new subclass of …

CANVAS 1: the first Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure …

GR Corey, MH Wilcox, GH Talbot, D Thye… - Journal of …, 2010 - academic.oup.com
Abstract Objectives Methicillin-resistant Staphylococcus aureus (MRSA) has emerged as a
common cause of complicated skin and skin structure infections (cSSSIs). Increasing …