Parkinson's disease (PD) is the most common neurodegenerative disorder with motor
symptoms. The neuropathological alterations characterizing the brain of patients with PD …

α-Synuclein (α-syn), a small highly conserved presynaptic protein containing 140 amino
acids, is thought to be the main pathological hallmark in related neurodegenerative …

Abstract α-Synuclein (α-Syn) is closely related to the pathogenesis of Parkinson's disease
(PD). Under pathological conditions, the conformation of α-syn changes and different forms …

Parkinson's disease (PD) is a complex neurodegenerative disease characterized by the
progressive loss of dopaminergic neurons in the substantia nigra and the widespread …

Alpha-synuclein (α-syn) is a small protein that, in neurons, localizes predominantly to
presynaptic terminals. Due to elevated conformational plasticity, which can be affected by …

Abstract α-Synuclein (α-Syn) has been extensively studied for its structural and biophysical
properties owing to its pathophysiological role in Parkinson's disease (PD). Lewy bodies …

Parkinson's disease (PD) is one of the synucleinopathies spectrum of disorders typified by
the presence of intraneuronal protein inclusions. It is primarily composed of misfolded and …

The development of novel therapies against neurodegenerative disorders requires the
ability to detect their early, presymptomatic manifestations in order to enable treatment …

Background: Parkinson's disease (PD) is a multifactorial, chronic, and progressive
neurodegenerative disease. α-Synuclein (α-syn), which is the main protein component of …

The aggregation of alpha synuclein (α‐syn) is a neuropathological feature that defines a
spectrum of disorders collectively termed synucleinopathies, and of these, Parkinson's …