Due to differences in anatomy, primary rectal and colon cancer require different staging
procedures, different neo-adjuvant treatment and different surgical approaches. For …

The management of rectal cancer has transformed over the last 3 decades and continues to
evolve. Some of these changes parallel progress made with other cancers: refinement of …

Primary treatment of rectal cancer was the focus of the second St. Gallen European
Organisation for Research and Treatment of Cancer (EORTC) Gastrointestinal Cancer …

Rectal adenocarcinoma is an important cause of cancer-related deaths worldwide, and key
anatomic differences between the rectum and the colon have significant implications for …

Colorectal cancer is one of the leading causes of cancer-related morbidity and mortality.
Main risk factors include advanced age, family history, male sex, and lifestyle factors …

Postoperative adjuvant chemoradiotherapy was recommended as the standard treatment for
patients with rectal cancer because it reduces local recurrence. This paradigm shifted with …

Aim Rectal cancer is a malignant disease requiring multidisciplinary management. In view of
the increasing number of studies published over the past decade, a comprehensive update …

Dramatic improvements in the outcomes of patients with rectal cancer have occurred over
the past 30 years. Advances in surgical pathology, refinements in surgical techniques and …

Simple Summary The outcome for patients with rectal cancer has significantly improved over
the last thirty years. Previously, local relapses in the pelvis occurred in more than one third of …

Rectal cancer treatment has evolved during the past 40 years with the use of a standardized
surgical technique for tumour resection: total mesorectal excision. A dramatic reduction in …