Background and purpose Local recurrences after radiotherapy for prostate cancer (PCa)
often originate at the location of the macroscopic tumour (s). Since PCa cells are known to …

Background Focal dose escalation in external beam radiotherapy (EBRT) showed an
increase in 5-yr biochemical disease-free survival in the Focal Lesion Ablative Microboost in …

Purpose To compare toxicity rates in patients with localized prostate cancer treated with
standard fractionated external beam radiotherapy (EBRT) with or without an additional …

Background There is growing evidence that prostate cancer (PC) cells are more sensitive to
high fraction dose in hypofractionation schemes. High-dose-rate (HDR) brachytherapy as …

PURPOSE This study investigates whether focal boosting of the macroscopic visible tumor
with external beam radiotherapy increases biochemical disease-free survival (bDFS) in …

Background The treatment results of external beam radiotherapy for intermediate and high
risk prostate cancer patients are insufficient with five-year biochemical relapse rates of …

Background Localised prostate cancer is commonly treated with external-beam
radiotherapy. Moderate hypofractionation has been shown to be non-inferior to conventional …

Purpose/Objective (s) External beam radiotherapy (EBRT) is a curative treatment for
Localized Prostate Cancer (LPCa). Large randomized controlled trials (RCTs) have shown …

Purpose Nowadays, advanced irradiation techniques make it possible to escalate safely the
dose in prostate cancer. We studied the effect of a higher dose on tumor control in a …

Background Prostate cancer might have high radiation-fraction sensitivity that would give a
therapeutic advantage to hypofractionated treatment. We present a pre-planned analysis of …