The vagus nerve mediates the suppressing effects of peripherally administered oxytocin on methamphetamine self-administration and seeking in rats

NA Everett, AJ Turner, PA Costa, SJ Baracz… - …, 2021 - nature.com
The neuropeptide oxytocin has emerged as a promising pharmacotherapy for
methamphetamine (METH) addiction, and clinical trials of intranasal oxytocin are underway …

Oxytocin decreases methamphetamine self-administration, methamphetamine hyperactivity, and relapse to methamphetamine-seeking behaviour in rats

DS Carson, JL Cornish, AJ Guastella, GE Hunt… - …, 2010 - Elsevier
There is emerging evidence that the neuropeptide oxytocin may be utilised as a treatment
for various psychopathologies, including drug addictions. Here we used an animal model to …

Oxytocin acts in nucleus accumbens to attenuate methamphetamine seeking and demand

BM Cox, BS Bentzley, H Regen-Tuero, RE See… - Biological …, 2017 - Elsevier
Background Evidence indicates that oxytocin, an endogenous peptide well known for its role
in social behaviors, childbirth, and lactation, is a promising addiction pharmacotherapy. We …

Oxytocin in the nucleus accumbens core reduces reinstatement of methamphetamine‐seeking behaviour in rats

SJ Baracz, NA Everett, IS McGregor… - Addiction …, 2016 - Wiley Online Library
The psychostimulant methamphetamine (METH) is an addictive illicit drug. Systemic
administration of the neuropeptide oxytocin modulates METH‐related reward and METH …

The role of the vasopressin V1A receptor in oxytocin modulation of methamphetamine primed reinstatement

NA Everett, IS McGregor, SJ Baracz, JL Cornish - Neuropharmacology, 2018 - Elsevier
The neuropeptide oxytocin has shown promise as an effective therapy in pre-clinical models
of methamphetamine (METH) addiction. The nucleus accumbens core (NAcc) has been …

Chronic methamphetamine treatment induces oxytocin receptor up-regulation in the amygdala and hypothalamus via an adenosine A2A receptor-independent …

P Zanos, SR Wright, P Georgiou, JH Yoo… - Pharmacology …, 2014 - Elsevier
There is mounting evidence that the neuropeptide oxytocin is a possible candidate for the
treatment of drug addiction. Oxytocin was shown to reduce methamphetamine self …

Systemically administered oxytocin decreases methamphetamine activation of the subthalamic nucleus and accumbens core and stimulates oxytocinergic neurons in …

DS Carson, GE Hunt, AJ Guastella, L Barber… - Addiction …, 2010 - Wiley Online Library
Recent preclinical evidence indicates that the neuropeptide oxytocin may have potential in
the treatment of drug dependence and drug withdrawal. Oxytocin reduces …

Oxytocin treatment in the prelimbic cortex reduces relapse to methamphetamine-seeking and is associated with reduced activity in the rostral nucleus accumbens core

N Everett, S Baracz, J Cornish - Pharmacology Biochemistry and Behavior, 2019 - Elsevier
Addiction to the psychostimulant Methamphetamine (METH) is characterised by high rates of
relapse. Currently there are no approved effective pharmacotherapies for METH …

Effects of oxytocin on methamphetamine-seeking exacerbated by predator odor pre-exposure in rats

CL Ferland, CM Reichel, JF McGinty - Psychopharmacology, 2016 - Springer
Rationale The endogenous oxytocin system has emerged as an inhibitor of drug-seeking
and stress in preclinical models. Objectives The goal of this study was to examine whether …

[HTML][HTML] The involvement of oxytocin in the subthalamic nucleus on relapse to methamphetamine-seeking behaviour

SJ Baracz, NA Everett, JL Cornish - PloS one, 2015 - journals.plos.org
The psychostimulant methamphetamine (METH) is an addictive drug of abuse. The
neuropeptide oxytocin has been shown to modulate METH-related reward and METH …