Currently, due to the increasing demand for 3D culture, various organoids that mimic organs
are being actively studied. Despite active reports, information on heart organoids (HOs) …

Human cardiac organoids (hCOs), three-dimensional (3D) cellular constructs similar to in
vivo organ, are new-generation models. To a large extent, a hCO retains the biological …

Recent progress in human organoids has provided 3D tissue systems to model human
development, diseases, as well as develop cell delivery systems for regenerative therapies …

Organoids are three-dimensional in vitro cell constructs that recapitulate organ properties
and structure to a significant extent. They constitute particularly useful models to study …

Cardiac organoids (COs) are miniaturized and simplified organ structures that can be used
in heart development biology, drug screening, disease modeling, and regenerative …

Cardiovascular diseases remain the leading cause of death worldwide; hence there is an
increasing focus on developing physiologically relevant in vitro cardiovascular tissue …

Induced pluripotent stem cells (iPSCs) have emerged as a key component of cardiac tissue
engineering, enabling studies of cardiovascular disease mechanisms, drug responses, and …

Engineered cardiac patches (ECPs) hold great promise to repair ischemia-induced
damages to the myocardium. Recent studies have provided robust technological advances …

An ensemble of in vitro cardiac tissue models has been developed over the past several
decades to aid our understanding of complex cardiovascular disorders using a reductionist …

The advent of human pluripotent stem cells (hPSCs) presented a new paradigm to employ
hPSC-derived cardiomyocytes (hPSC-CMs) in drug screening and disease modeling …