Mechanisms of small cell lung cancer metastasis

J Ko, MM Winslow, J Sage - EMBO molecular medicine, 2021 - embopress.org
Metastasis is a major cause of morbidity and mortality in cancer patients. However, the
molecular and cellular mechanisms underlying the ability of cancer cells to metastasize …

Advances in small-cell lung cancer (SCLC) translational research

BJ Drapkin, CM Rudin - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
Over the past several years, we have witnessed a resurgence of interest in the biology and
therapeutic vulnerabilities of small-cell lung cancer (SCLC). This has been driven in part …

Small cell lung cancer: will recent progress lead to improved outcomes?

MC Pietanza, LA Byers, JD Minna, CM Rudin - Clinical Cancer Research, 2015 - AACR
Small cell lung cancer (SCLC) is an aggressive neuroendocrine malignancy with a unique
natural history characterized by a short doubling time, high growth fraction, and early …

[HTML][HTML] Small cell lung cancer (SCLC): no treatment advances in recent years

F Koinis, A Kotsakis, V Georgoulias - Translational lung cancer …, 2016 - ncbi.nlm.nih.gov
Small cell lung cancer (SCLC) is an aggressive malignancy with a distinct natural history
and dismal prognosis. Given its predisposition for early dissemination, patients are …

Epigenetic landscape of small cell lung cancer: small image of a giant recalcitrant disease

P Khan, JA Siddiqui, SK Maurya, I Lakshmanan… - Seminars in cancer …, 2022 - Elsevier
Small cell lung cancer (SCLC) is a particular subtype of lung cancer with high mortality.
Recent advances in understanding SCLC genomics and breakthroughs of immunotherapy …

Origins, genetic landscape, and emerging therapies of small cell lung cancer

EA Semenova, R Nagel, A Berns - Genes & development, 2015 - genesdev.cshlp.org
Lung cancer is the leading cause of cancer deaths, with small cell lung cancer (SCLC)
representing the most aggressive subtype. Standard treatments have not changed in …

[HTML][HTML] Small cell lung cancer: can recent advances in biology and molecular biology be translated into improved outcomes?

PA Bunn Jr, JD Minna, A Augustyn, AF Gazdar… - Journal of Thoracic …, 2016 - Elsevier
Small cell lung cancer (SCLC) is one of the four major histological types of lung cancer. The
incidence of SCLC in developed countries has declined in recent years, presumably …

[HTML][HTML] Cellular and molecular biology of small cell lung cancer: an overview

N Karachaliou, S Pilotto, C Lazzari, E Bria… - … lung cancer research, 2016 - ncbi.nlm.nih.gov
Although the incidence of small cell lung cancer (SCLC) has declined during the past 30
years, it remains a frustrating disease to research and treat. Numerous attempts to enhance …

Small cell lung cancer: where do we go from here?

LA Byers, CM Rudin - Cancer, 2015 - Wiley Online Library
Small cell lung cancer (SCLC) is an aggressive disease that accounts for approximately
14% of all lung cancers. In the United States, approximately 31,000 patients are diagnosed …

Molecular subtyping of small cell lung cancer

J Liang, X Guan, G Bao, Y Yao, X Zhong - Seminars in Cancer Biology, 2022 - Elsevier
Small cell lung cancer (SCLC), originating from lung neuroendocrine stem cells, is a
common pulmonary malignant tumor. SCLC, with poor prognoses, accounts for …