Abstract Type I interferon (IFN-I) plays crucial roles in the regulation of inflammation and it is
associated with various inflammatory diseases including systemic lupus erythematosus …

Although contributing to inflammatory responses and to the development of certain
autoimmune pathologies, type I interferons (IFNs) are used for the treatment of viral …

Type I interferons (IFNs) play essential roles in establishing and modulating host defense
against microbial infection via induction of IFN-stimulated genes (ISGs) through Janus …

Interleukin-1β (IL-1β) and type I interferons (IFNs) are major cytokines involved in
autoinflammatory/autoimmune diseases. Separately, the overproduction of each of these …

Production of interferon-γ (IFNγ) in response to infection is a hallmark of innate and adaptive
immunity. In addition to the pivotal role of IFNγ in host defense, its excessive release has …

Interferons (IFNs) are very powerful cytokines, which play a key role in combatting pathogen
infections by controlling inflammation and immune response by directly inducing anti …

IFN-γ is an extraordinarily pleotropic cytokine. It can not only heighten both the innate and
adaptive immune response against pathogens and tumors, but also has the ability to …

More than 60 years ago a soluble factor which “interferes” with influenza virus infection was
discovered named “interferon”. Since then the fascinating complex biology of type I …

The type I interferon (IFN) system is our main defense against viral infections and consists of
a large number of sensors of nucleic acid that can trigger the production of more than 15 …

Cytokines are pleiotropic molecules showing a wide variety of biologic functions on various
cells and tissues, and several different cytokines exert similar and overlapping functions on …