Endophytic fungi: Key insights, emerging prospects, and challenges in natural product drug discovery

P Tiwari, H Bae - Microorganisms, 2022 - mdpi.com
Plant-associated endophytes define an important symbiotic association in nature and are
established bio-reservoirs of plant-derived natural products. Endophytes colonize the …

Bioactive secondary metabolites from endophytic fungi

E Ancheeva, G Daletos… - Current medicinal …, 2020 - ingentaconnect.com
Background: Endophytes represent a complex community of microorganisms colonizing
asymptomatically internal tissues of higher plants. Several reports have shown that …

Fungal endophytes: Microfactories of novel bioactive compounds with therapeutic interventions; A comprehensive review on the biotechnological developments in the …

A Gupta, V Meshram, M Gupta, S Goyal, KA Qureshi… - Biomolecules, 2023 - mdpi.com
The seminal discovery of paclitaxel from endophytic fungus Taxomyces andreanae was a
milestone in recognizing the immense potential of endophytic fungi as prolific producers of …

Fungal endophytes: A promising frontier for discovery of novel bioactive compounds

MM Gakuubi, M Munusamy, ZX Liang, SB Ng - Journal of fungi, 2021 - mdpi.com
For years, fungi have served as repositories of bioactive secondary metabolites that form the
backbone of many existing drugs. With the global rise in infections associated with …

Chemical ecology of endophytic fungi: origins of secondary metabolites

S Kusari, C Hertweck, M Spiteller - Chemistry & biology, 2012 - cell.com
Endophytes constitute a remarkably multifarious group of microorganisms ubiquitous in
plants and maintain an imperceptible association with their hosts for at least a part of their …

Bioactive secondary metabolites from endophytic fungi: a review of biotechnological production and their potential applications

RH Patil, MP Patil, VL Maheshwari - Studies in natural products chemistry, 2016 - Elsevier
New viral diseases, multidrug-resistant microorganisms, and infections by uncommon
pathogens are emerging as new threats to human, plant, and animal health. Therefore, there …

Secondary metabolites from endophytic fungi: Production, methods of analysis, and diverse pharmaceutical potential

VK Singh, A Kumar - Symbiosis, 2023 - Springer
The synthesis of secondary metabolites is a constantly functioning metabolic pathway in all
living systems. Secondary metabolites can be broken down into numerous classes …

Endophytic fungi: An effective alternative source of plant-derived bioactive compounds for pharmacological studies

J Wen, SK Okyere, S Wang, J Wang, L Xie, Y Ran… - Journal of Fungi, 2022 - mdpi.com
Plant-associated fungi (endophytic fungi) are a biodiversity-rich group of microorganisms
that are normally found asymptomatically within plant tissues or in the intercellular spaces …

Untapped potentials of endophytic fungi: A review of novel bioactive compounds with biological applications

MC Manganyi, CN Ateba - Microorganisms, 2020 - mdpi.com
Over the last century, endophytic fungi have gained tremendous attention due to their ability
to produce novel bioactive compounds exhibiting varied biological properties and are …

Fungal endophytes as efficient sources of plant-derived bioactive compounds and their prospective applications in natural product drug discovery: Insights, avenues …

A Singh, DK Singh, RN Kharwar, JF White, SK Gond - Microorganisms, 2021 - mdpi.com
Fungal endophytes are well-established sources of biologically active natural compounds
with many producing pharmacologically valuable specific plant-derived products. This …