Tumor necrosis factor (TNF) and its receptors are widely expressed in non-small cell lung
cancer (NSCLC). TNF has an established role in inflammation and also plays a key role in …

BACKGROUND In vitro studies have shown an antiproliferative effect of tumor necrosis
factor (TNF) against various nonsmall cell lung carcinoma (NSCLC) cell lines. However …

Tumor necrosis factor (TNF) is a cytokine with well known anticancer properties and is being
utilized as anticancer agent for the treatment of patients with locally advanced solid tumors …

Tumor necrosis factor (TNF) is a multifunctional cytokine that plays important roles in diverse
cellular events such as cell survival, proliferation, differentiation, and death. As a pro …

Almost two decades ago, tumor necrosis factor (TNF) was identified as a protein produced
by the immune system that played a major role in suppression of tumor cell proliferation …

Thirty-four years since its discovery, NF-κB remains a transcription factor with great potential
for cancer therapy. However, NF-κB–targeted therapies have yet to find a way to be clinically …

Tumor necrosis factor (TNF) is being utilized as an antineoplastic agent for the treatment of
patients with locally advanced solid tumors. However, its role in cancer therapy is debated …

Tumor necrosis factor (TNF) is the name of an activity produced by activated macrophages
that induced hemorrhagic necrosis of transplanted tumors in mice and killed transformed cell …

Tumor necrosis factor-alpha (TNFα) can bind two distinct receptors (TNFR1/2). The
transmembrane form (tmTNFα) preferentially binds to TNFR2. Upon tmTNFα cleavage by the …

The potent pro-inflammatory cytokine tumor necrosis factor α (TNFα) has been connected to
cancer progression and treatment ever since its discovery as a major factor contributing to …