COX-2/EGFR expression and survival among women with adenocarcinoma of the lung
AL Van Dyke, ML Cote, GM Prysak, GB Claeys… - …, 2008 - academic.oup.com
Previous studies suggest that cyclooxygenase-2 (COX-2) expression may predict survival
among patients with non-small cell lung cancer. COX-2 may interact with epidermal growth …
among patients with non-small cell lung cancer. COX-2 may interact with epidermal growth …
Co-expression of Cox-2 and EGFR in stage I human bronchial adenocarcinomas
K Araki, K Hashimoto, TD Ardyanto, M Osaki… - Lung Cancer, 2004 - Elsevier
Cyclooxygenase (Cox)-2 plays an important role in cell proliferation, carcinogenesis and
tumor growth, in part through the synthesis of prostaglandin E2 (PGE2) as well as through …
tumor growth, in part through the synthesis of prostaglandin E2 (PGE2) as well as through …
Prognostic significance of cyclooxygenase 2 expression in 259 cases of non–small cell lung cancer
AC Laga, DS Zander, PT Cagle - Archives of pathology & …, 2005 - meridian.allenpress.com
Context.—Previous studies report that increased expression of cyclooxygenase 2 (COX-2)
correlates with poor clinical outcome in several malignancies, including non–small cell lung …
correlates with poor clinical outcome in several malignancies, including non–small cell lung …
Prognostic significance of elevated cyclooxygenase 2 expression in primary, resected lung adenocarcinomas
Recently, we demonstrated that elevated expression of cyclooxygenase 2 (COX-2) is
frequently seen in a specific type of lung cancer, ie, adenocarcinoma, and is possibly …
frequently seen in a specific type of lung cancer, ie, adenocarcinoma, and is possibly …
Cyclooxygenase-2 protein levels are independent of epidermal growth factor receptor expression or activation in operable non-small cell lung cancer
CM Richardson, D Richardson, DEB Swinson… - Lung Cancer, 2005 - Elsevier
Both cyclooxygenase (COX)-2 and epidermal growth factor receptor (EGFR) are thought to
play important roles in the pathogenesis of non-small cell lung cancer (NSCLC). A number …
play important roles in the pathogenesis of non-small cell lung cancer (NSCLC). A number …
Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer
Abstract Cyclooxygenase-2 (COX-2), the enzyme that converts arachidonic acid to
prostaglandins, is overexpressed in a variety of different tumors, including those of the colon …
prostaglandins, is overexpressed in a variety of different tumors, including those of the colon …
[HTML][HTML] Has Cox-2 a prognostic role in non-small-cell lung cancer? A systematic review of the literature with meta-analysis of the survival results
C Mascaux, B Martin, M Paesmans… - British journal of …, 2006 - nature.com
Abstract Cyclooxygenase-2 (COX-2) is overexpressed in lung cancer, especially in
adenocarcinoma (ADC). Our aim was to determine the prognostic value of COX-2 on …
adenocarcinoma (ADC). Our aim was to determine the prognostic value of COX-2 on …
Cox-2 in non-small cell lung cancer: a meta-analysis
H Jiang, J Wang, W Zhao - Clinica chimica acta, 2013 - Elsevier
BACKGROUND: We investigated the prognostic value of cyclooxygenase-2 (COX-2) for
survival of patients with non-small cell lung cancer (NSCLC). METHODS: We performed a …
survival of patients with non-small cell lung cancer (NSCLC). METHODS: We performed a …
[HTML][HTML] EGFR and COX-2 protein expression in non-small cell lung cancer and the correlation with clinical features
F Li, Y Liu, H Chen, D Liao, Y Shen, F Xu… - Journal of Experimental & …, 2011 - Springer
Background To evaluate the expression of EGFR and COX-2 and their correlation with
prognosis in NSCLC Methods The paraffin embedded tumor samples of 50 NSCLC patients …
prognosis in NSCLC Methods The paraffin embedded tumor samples of 50 NSCLC patients …
COX-2 expression during early lung squamous cell carcinoma oncogenesis
C Mascaux, B Martin, JM Verdebout… - European …, 2005 - Eur Respiratory Soc
Cyclooxygenase (COX)-2 is implicated in the oncogenesis of many cancers, and COX-2
inhibitors are effective in preventing the development of tumours, such as in colon cancer. Its …
inhibitors are effective in preventing the development of tumours, such as in colon cancer. Its …