The long slender bloodstream form Trypanosoma brucei maintains its essential
mitochondrial membrane potential (ΔΨm) through the proton-pumping activity of the FoF1 …

In the infectious stage of Trypanosoma brucei, an important parasite of humans and
livestock, the mitochondrial (mt) membrane potential (Δψm) is uniquely maintained by the …

Mitochondrial ATP synthase is a reversible nanomotor synthesizing or hydrolyzing ATP
depending on the potential across the membrane in which it is embedded. In the unicellular …

The unicellular parasite Trypanosoma brucei has a digenetic life cycle that alternates
between a mammalian host and an insect vector. During programmed development, this …

The mitochondrial (mt) FoF1-ATP synthase of the digenetic parasite, Trypanosoma brucei,
generates ATP during the insect procyclic form (PF), but becomes a perpetual consumer of …

The mitochondrion of Trypanosoma brucei bloodstream form maintains a membrane
potential, although it lacks cytochromes and several Krebs cycle enzymes. At this stage, the …

The mitochondrion is crucial for ATP generation by oxidative phosphorylation, among other
processes. Cristae are invaginations of the mitochondrial inner membrane that house nearly …

Viability of the tsetse fly-transmitted African trypanosome Trypanosoma brucei depends on
maintenance and expression of its kinetoplast (kDNA), the mitochondrial genome of this …

Trypanosoma brucei is a parasitic protist that causes significant health burden in sub-
Saharan countries endemic for the tsetse fly (Glossina spp.). During the bloodmeal of this …

Trypanosoma cruzi is the kinetoplastid protozoan parasite that causes human Chagas
disease, a chronic disease with complex outcomes including severe cardiomyopathy and …