A cross-talk about radioresistance in lung cancer—How to improve radiosensitivity according to Chinese medicine and medicaments that commonly occur in …

P Nowak, I Bil-Lula, M Śliwińska-Mossoń - International Journal of …, 2023 - mdpi.com
Lung cancer is one of the most common cancers in the population and is characterized by
non-specific symptoms that delay the diagnosis and reduce the effectiveness of oncological …

Therapeutic implications for overcoming radiation resistance in cancer therapy

BM Kim, Y Hong, S Lee, P Liu, JH Lim, YH Lee… - International journal of …, 2015 - mdpi.com
Ionizing radiation (IR), such as X-rays and gamma (γ)-rays, mediates various forms of cancer
cell death such as apoptosis, necrosis, autophagy, mitotic catastrophe, and senescence …

Investigation of radiation-induced transcriptome profile of radioresistant non-small cell lung cancer A549 cells using RNA-seq

HJ Yang, N Kim, KM Seong, HS Youn, BH Youn - PloS one, 2013 - journals.plos.org
Radioresistance is a main impediment to effective radiotherapy for non-small cell lung
cancer (NSCLC). Despite several experimental and clinical studies of resistance to …

chemo-radiation-resistance in cancer therapy

X Lin, D Kong, ZS Chen - Frontiers in pharmacology, 2022 - frontiersin.org
In recent years, technical advances in chemotherapy and radiotherapy have helped
substantially improve the treatment outcome and quality of life of cancer patients …

Factors and molecular mechanisms of radiation resistance in cancer cells

JC Alamilla-Presuel, AM Burgos-Molina… - … Journal of Radiation …, 2022 - Taylor & Francis
Purpose The aim of this work is to review the published studies on radiation resistance
mechanisms and molecular markers involved in different tumors. The revision has been …

Biological mechanisms to reduce radioresistance and increase the efficacy of radiotherapy: state of the art

F Busato, BE Khouzai, M Mognato - International journal of molecular …, 2022 - mdpi.com
Cancer treatment with ionizing radiation (IR) is a well-established and effective clinical
method to fight different types of tumors and is a palliative treatment to cure metastatic …

Clinically relevant radioresistant cell line: a simple model to understand cancer radioresistance

Y Kuwahara, MH Roudkenar, Y Urushihara… - Medical Molecular …, 2017 - Springer
Radiotherapy (RT) is one of the major modalities for the treatment of human cancers and
has been established as an excellent local treatment for malignant tumors. Conventional …

'Stemness' and 'senescence'related escape pathways are dose dependent in lung cancer cells surviving post irradiation

A Tsolou, I Lamprou, AO Fortosi, M Liousia… - Life sciences, 2019 - Elsevier
Aims Lung cancer is one of the main causes of cancer-related deaths worldwide and
radiotherapy is a major treatment of choice. However, radioresistance is a main reason for …

[HTML][HTML] Cancer stem cells and signaling pathways in radioresistance

L Chang, P Graham, J Hao, J Ni, J Deng, J Bucci… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Radiation therapy (RT) is one of the most important strategies in cancer treatment.
Radioresistance (the failure to RT) results in locoregional recurrence and metastasis …

Molecular determinants of radiosensitivity in normal and tumor tissue: A bioinformatic approach

A Pavlopoulou, PG Bagos, V Koutsandrea… - Cancer letters, 2017 - Elsevier
Although radiation therapy is a treatment of choice for cancer, a high percentage of patients
develop adverse effects in normal tissue following radiotherapy, mainly, due to genetic …