Osteochondral defect management and repair remain a significant challenge in orthopedic
surgery. Osteochondral defects contain damage to both the articular cartilage as well as the …

Purpose Osteochondral defects (ie, defects which affect both the articular cartilage and
underlying subchondral bone) are often associated with mechanical instability of the joint …

People suffering from pain due to osteoarthritic or rheumatoidal changes in the joints are still
waiting for a better treatment. Although some studies have achieved success in repairing …

Critical‐sized osteochondral defects are clinically challenging, with limited treatment options
available. By engineering osteochondral grafts using a patient's own cells and …

Over centuries, several advances have been made in osteochondral (OC) tissue
engineering to regenerate more biomimetic tissue. As an essential component of tissue …

In spite of the considerable achievements in the field of regenerative medicine in the past
several decades, osteochondral defect regeneration remains a challenging issue among …

The management of osteoarthritis (OA) remains challenging and controversial. Although
several clinical options exist for the treatment of OA, regeneration of the damaged articular …

Interest in osteochondral repair has been increasing with the growing number of sports-
related injuries, accident traumas, and congenital diseases and disorders. Although …

Clinical treatments for the repair of osteochondral defects (OCD) are merely palliative, not
completely curative, and thus enormously unfulfilled challenges. With the in‐depth studies of …

Articular cartilage is often damaged due to trauma or degenerative diseases, resulting in
severe pain and disability. Most clinical approaches have been shown to have limited …