Background Optimal ambulatory reflux monitoring methodology in symptomatic reflux
patients continues to be debated. Aims To utilise published literature and expert opinion to …

Background and Aims Acid exposure time (AET) and reflux episode thresholds from the
Lyon Consensus may not apply for pH impedance studies performed while on proton pump …

Background Refractory reflux‐like symptoms have a substantial impact on patients and
healthcare providers. The aim of the survey was to qualitatively assess the needs and …

Background and Aims Proton pump inhibitor (PPI) therapy fails to provide adequate
symptom control in up to 50% of patients with gastroesophageal reflux symptoms. Although …

Background Genesis of persistent gastro‐esophageal reflux symptoms despite proton pump
inhibitor (PPI) therapy is not fully understood. We aimed at determining reflux patterns on 24 …

METHODS: This single-arm clinical trial performed over 4 years at 2 centers enrolled adults
with troublesome GERD symptoms and inadequate response to> 8 weeks of PPI …

Diagnosing gastroesophageal reflux disease (GERD) often entails using a combination of
patient symptoms, response to proton pump inhibitors (PPI), upper endoscopy, and …

Gastroesophagel reflux disease (GERD) is a common condition encountered in clinical
practice. Over the years there has been a continuous interaction between the understanding …

Background Both simple proportions and statistical tests are utilised for symptom‐reflux
association. We systematically compared three such tests in a clinical setting. Aim To …

Purpose: Refluxate with a pH> 4 (“non-acid” reflux, NAR) cannot be detected on standard
esophageal pH monitoring. However this can be overcome by the use of Multichannel …