Necroptosis in development, inflammation and disease
R Weinlich, A Oberst, HM Beere… - Nature reviews Molecular …, 2017 - nature.com
In the early 2000s, receptor-interacting serine/threonine protein kinase 1 (RIPK1), a
molecule already recognized as an important regulator of cell survival, inflammation and …
molecule already recognized as an important regulator of cell survival, inflammation and …
Necroptosis in development and diseases
Necroptosis, a form of regulated necrotic cell death mediated by RIPK1 (receptor-interacting
protein kinase 1) kinase activity, RIPK3, and MLKL (mixed-lineage kinase domain-like …
protein kinase 1) kinase activity, RIPK3, and MLKL (mixed-lineage kinase domain-like …
The inflammatory signal adaptor RIPK3: functions beyond necroptosis
K Moriwaki, FKM Chan - International review of cell and molecular biology, 2017 - Elsevier
Receptor interacting protein kinase 3 (RIPK3) is an essential serine/threonine kinase for
necroptosis, a type of regulated necrosis. A variety of stimuli can cause RIPK3 activation …
necroptosis, a type of regulated necrosis. A variety of stimuli can cause RIPK3 activation …
Necroptosis and inflammation
K Newton, G Manning - Annual review of biochemistry, 2016 - annualreviews.org
Necroptosis is a regulated form of necrosis, with the dying cell rupturing and releasing
intracellular components that can trigger an innate immune response. Toll-like receptor 3 …
intracellular components that can trigger an innate immune response. Toll-like receptor 3 …
[HTML][HTML] Initiation and execution mechanisms of necroptosis: an overview
S Grootjans, T Vanden Berghe… - Cell Death & …, 2017 - nature.com
Necroptosis is a form of regulated cell death, which is induced by ligand binding to TNF
family death domain receptors, pattern recognizing receptors and virus sensors. The …
family death domain receptors, pattern recognizing receptors and virus sensors. The …
Complex pathologic roles of RIPK1 and RIPK3: moving beyond necroptosis
KW Wegner, D Saleh, A Degterev - Trends in pharmacological sciences, 2017 - cell.com
A process of regulated necrosis, termed necroptosis, has been recognized as a major
contributor to cell death and inflammation occurring under a wide range of pathologic …
contributor to cell death and inflammation occurring under a wide range of pathologic …
A toolbox for imaging RIPK1, RIPK3, and MLKL in mouse and human cells
AL Samson, C Fitzgibbon, KM Patel… - Cell Death & …, 2021 - nature.com
Necroptosis is a lytic, inflammatory cell death pathway that is dysregulated in many human
pathologies. The pathway is executed by a core machinery comprising the RIPK1 and …
pathologies. The pathway is executed by a core machinery comprising the RIPK1 and …
The regulation of necroptosis by post-translational modifications
Necroptosis is a caspase-independent, lytic form of programmed cell death whose errant
activation has been widely implicated in many pathologies. The pathway relies on the …
activation has been widely implicated in many pathologies. The pathway relies on the …
[HTML][HTML] Necroptosis: a regulated inflammatory mode of cell death
YK Dhuriya, D Sharma - Journal of neuroinflammation, 2018 - Springer
Programmed cell death has a vital role in embryonic development and tissue homeostasis.
Necroptosis is an alternative mode of regulated cell death mimicking features of apoptosis …
Necroptosis is an alternative mode of regulated cell death mimicking features of apoptosis …
RIPK1 and RIPK3: critical regulators of inflammation and cell death
K Newton - Trends in cell biology, 2015 - cell.com
RIPK1 and RIPK3 (receptor-interacting serine/threonine protein kinases 1/3) interact by
virtue of their RIP homotypic interaction motifs to mediate a form of cell death called …
virtue of their RIP homotypic interaction motifs to mediate a form of cell death called …