Aptamer-based assembly systems for SARS-CoV-2 detection and therapeutics
Y Dong, J Wang, L Chen, H Chen, S Dang… - Chemical Society …, 2024 - pubs.rsc.org
Nucleic acid aptamers are oligonucleotide chains with molecular recognition properties.
Compared with antibodies, aptamers show advantages given that they are readily produced …
Compared with antibodies, aptamers show advantages given that they are readily produced …
Harnessing aptamers against COVID-19: A therapeutic strategy
A Mahmoudi, SH Alavizadeh, SA Hosseini… - Drug Discovery …, 2023 - Elsevier
Highlights•The novel coronavirus crisis caused by SARS-CoV-2 affected the world as a
global pandemic.•Aptamers are single-stranded RNA or DNA oligonucleotides or peptide …
global pandemic.•Aptamers are single-stranded RNA or DNA oligonucleotides or peptide …
Engineered aptamers for enhanced COVID-19 theranostics
Introduction The 2019-novel coronavirus disease (COVID-19) is an intractable global health
challenge resulting in an aberrant rate of morbidity and mortality worldwide. The mode of …
challenge resulting in an aberrant rate of morbidity and mortality worldwide. The mode of …
[HTML][HTML] Aptamer-Mediated Antiviral Approaches for SARS-CoV-2
2020 and 2021 were disastrous years across the world, with the emergence of the severe
acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) virus as a pandemic, which …
acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) virus as a pandemic, which …
Aptamer‐Based Strategies to Address Challenges in COVID‐19 Diagnosis and Treatments
ZY Chang, FAMS Alhamami… - … Perspectives on Infectious …, 2023 - Wiley Online Library
Coronavirus disease (COVID‐19), a highly contagious and rapidly spreading disease with
significant fatality in the elderly population, has swept across the world since 2019. Since its …
significant fatality in the elderly population, has swept across the world since 2019. Since its …
Structure-Guided Development of Bivalent Aptamers Blocking SARS-CoV-2 Infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused devastation to
human society through its high virulence, infectivity, and genomic mutations, which reduced …
human society through its high virulence, infectivity, and genomic mutations, which reduced …
Net-shaped DNA nanostructures designed for rapid/sensitive detection and potential inhibition of the SARS-CoV-2 virus
We present a net-shaped DNA nanostructure (called “DNA Net” herein) design strategy for
selective recognition and high-affinity capture of intact SARS-CoV-2 virions through spatial …
selective recognition and high-affinity capture of intact SARS-CoV-2 virions through spatial …
Aptamers as promising nanotheranostic tools in the COVID‐19 pandemic era
CKO Dzuvor, EL Tettey… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
The emergence of SARS‐COV‐2, the causative agent of new coronavirus disease (COVID‐
19) has become a pandemic threat. Early and precise detection of the virus is vital for …
19) has become a pandemic threat. Early and precise detection of the virus is vital for …
Robust covalent aptamer strategy enables sensitive detection and enhanced inhibition of SARS-CoV-2 proteins
Aptamer-based detection and therapy have made substantial progress with cost control and
easy modification. However, the conformation lability of an aptamer typically causes the …
easy modification. However, the conformation lability of an aptamer typically causes the …
Aptamers—diagnostic and therapeutic solution in SARS-CoV-2
T Wandtke, E Wędrowska, M Szczur… - International journal of …, 2022 - mdpi.com
The SARS-CoV-2 virus is currently the most serious challenge to global public health. Its
emergence has severely disrupted the functioning of health services and the economic and …
emergence has severely disrupted the functioning of health services and the economic and …