Induction of anti‐HIV neutralizing antibodies by synthetic peptides.

TC Chanh, GR Dreesman, P Kanda, GP Linette… - The EMBO …, 1986 - embopress.org
Two synthetic peptides containing amino acid sequences analogous to the envelope
glycoprotein of human T‐lymphotropic virus (HTLV) type III (HTLV‐III) and lymphadenopathy …

Antiserum to a synthetic peptide recognizes the HTLV-III envelope glycoprotein

RC Kennedy, RD Henkel, D Pauletti, JS Allan, TH Lee… - Science, 1986 - science.org
In a study performed to determine which regions of the human T-cell lymphotrophic virus
type III (HTLV-III) may represent vaccine candidates to prevent the acquired immune …

Type-specific neutralization of the human immunodeficiency virus with antibodies to env-encoded synthetic peptides.

TJ Palker, ME Clark, AJ Langlois… - Proceedings of the …, 1988 - National Acad Sciences
A synthetic peptide (SP-10-IIIB) with an amino acid sequence [Cys-Thr-Arg-Pro-Asn-Asn-
Asn-Thr-Arg-Lys-Ser-Ile-Arg-Ile-Gln-Arg-Gly-Pro-Pro-Gly-(Tyr); amino acids 303-321] from …

Characterization of a human immunodeficiency virus neutralizing monoclonal antibody and mapping of the neutralizing epitope

S Matsushita, M Robert-Guroff, J Rusche… - Journal of …, 1988 - Am Soc Microbiol
A monoclonal antibody was produced to the exterior envelope glycoprotein (gp120) of the
human T-cell lymphotropic virus (HTLV)-IIIB isolate of the human immunodeficiency virus …

Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III

JS Allan, JE Coligan, F Barin, MF McLane, JG Sodroski… - Science, 1985 - science.org
Antibodies from the serum of patients with the acquired immune deficiency syndrome (AIDS)
or with the AIDS-related complex and from the serum of seropositive healthy homosexuals …

HTLV-III/LAV-Neutralizing Antibodies to an E. coli-Produced Fragment of the Virus Envelope

SD Putney, TJ Matthews, WG Robey, DL Lynn… - Science, 1986 - science.org
Immunization with either an Escherichia coli recombinant segment of the human T-cell
lymphotropic virus (HTLV-III/LAV) envelope protein (gp120) or with deglycosylated gp120 …

Synthetic peptides containing T and B cell epitopes from human immunodeficiency virus envelope gp120 induce anti-HIV proliferative responses and high titers of …

MK Hart, TJ Palker, TJ Matthews… - … (Baltimore, Md.: 1950 …, 1990 - journals.aai.org
We have previously described a synthetic peptide (T1-SP10) derived from two
noncontiguous regions of HTLVIIIB envelope gp120 (T1, amino acids 428-443; SP10, amino …

Polyvalent human immunodeficiency virus synthetic immunogen comprised of envelope gp120 T helper cell sites and B cell neutralization epitopes.

TJ Palker, TJ Matthews, A Langlois… - … (Baltimore, Md.: 1950 …, 1989 - journals.aai.org
In previous studies, we have used antisera raised to envelope (env)-gene-encoded
synthetic peptides to identify a region of (HIV) glycoprotein (gp) 120 env protein designated …

Helper T-cell antigenic site identification in the acquired immunodeficiency syndrome virus gp120 envelope protein and induction of immunity in mice to the native …

KB Cease, H Margalit, JL Cornette… - Proceedings of the …, 1987 - National Acad Sciences
Much effort has been devoted to the analysis of antibodies to acquired immunodeficiency
syndrome virus antigens, but no studies, to our knowledge, have defined antigenic sites of …

Detection of antibodies to human T-lymphotropic virus type III by using a synthetic peptide of 21 amino acid residues corresponding to a highly antigenic segment of …

JJ Wang, S Steel, R Wisniewolski… - Proceedings of the …, 1986 - National Acad Sciences
A peptide of 21 amino acids with the sequence Arg-Ile-Leu-Ala-Val-Glu-Arg-Tyr-Leu-Lys-
Asp-Gln-Gln-Leu-Leu-Gly-Ile-Trp-Gly-Cys-Ser encoded by a segment in the env gene of …