A universal and robust integrated platform for the scalable production of human cardiomyocytes from pluripotent stem cells
H Fonoudi, H Ansari, S Abbasalizadeh… - Stem cells …, 2015 - academic.oup.com
Recent advances in the generation of cardiomyocytes (CMs) from human pluripotent stem
cells (hPSCs), in conjunction with the promising outcomes from preclinical and clinical …
cells (hPSCs), in conjunction with the promising outcomes from preclinical and clinical …
[HTML][HTML] Development of a scalable suspension culture for cardiac differentiation from human pluripotent stem cells
VC Chen, J Ye, P Shukla, G Hua, D Chen, Z Lin, J Liu… - Stem cell …, 2015 - Elsevier
To meet the need of a large quantity of hPSC-derived cardiomyocytes (CM) for pre-clinical
and clinical studies, a robust and scalable differentiation system for CM production is …
and clinical studies, a robust and scalable differentiation system for CM production is …
Considerations in designing systems for large scale production of human cardiomyocytes from pluripotent stem cells
A Chen, S Ting, J Seow, S Reuveny, S Oh - Stem cell research & therapy, 2014 - Springer
Human pluripotent stem cell (hPSC)-derived cardiomyocytes have attracted attention as an
unlimited source of cells for cardiac therapies. One of the factors to surmount to achieve this …
unlimited source of cells for cardiac therapies. One of the factors to surmount to achieve this …
Cardiac differentiation of human pluripotent stem cells in scalable suspension culture
H Kempf, C Kropp, R Olmer, U Martin, R Zweigerdt - Nature protocols, 2015 - nature.com
Cardiomyocytes (CMs) generated from human pluripotent stem cells (hPSCs) are a potential
cell source for regenerative therapies, drug discovery and disease modeling. All these …
cell source for regenerative therapies, drug discovery and disease modeling. All these …
Human cardiomyocyte generation from pluripotent stem cells: A state-of-art
The human heart is considered a non-regenerative organ. Worldwide, cardiovascular
diseases continue to be the leading cause of death. Despite advances in cardiac treatment …
diseases continue to be the leading cause of death. Despite advances in cardiac treatment …
Standardized production of hPSC-derived cardiomyocyte aggregates in stirred spinner flasks
N Kriedemann, W Triebert, J Teske, M Mertens… - Nature …, 2024 - nature.com
A promising cell-therapy approach for heart failure aims at differentiating human pluripotent
stem cells (hPSCs) into functional cardiomyocytes (CMs) in vitro to replace the disease …
stem cells (hPSCs) into functional cardiomyocytes (CMs) in vitro to replace the disease …
Large-scale production of human pluripotent stem cell derived cardiomyocytes
H Kempf, B Andree, R Zweigerdt - Advanced Drug Delivery Reviews, 2016 - Elsevier
Regenerative medicine, including preclinical studies in large animal models and tissue
engineering approaches as well as innovative assays for drug discovery, will require the …
engineering approaches as well as innovative assays for drug discovery, will require the …
A massive suspension culture system with metabolic purification for human pluripotent stem cell-derived cardiomyocytes
N Hemmi, S Tohyama, K Nakajima… - Stem cells …, 2014 - academic.oup.com
Cardiac regenerative therapy with human pluripotent stem cells (hPSCs), such as human
embryonic stem cells and induced pluripotent stem cells, has been hampered by the lack of …
embryonic stem cells and induced pluripotent stem cells, has been hampered by the lack of …
Maturation of pluripotent stem cell-derived cardiomyocytes: a critical step for drug development and cell therapy
SH Tan, L Ye - Journal of cardiovascular translational research, 2018 - Springer
Cardiomyocytes derived from human pluripotent stem cells (hPSCs) are emerging as an
invaluable alternative to primarily sourced cardiomyocytes. The potentially unlimited number …
invaluable alternative to primarily sourced cardiomyocytes. The potentially unlimited number …
[HTML][HTML] Current strategies and challenges for purification of cardiomyocytes derived from human pluripotent stem cells
Cardiomyocytes (CMs) derived from human pluripotent stem cells (hPSCs) are considered a
most promising option for cell-based cardiac repair. Hence, various protocols have been …
most promising option for cell-based cardiac repair. Hence, various protocols have been …
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