Biomedical Potential of Keratin-Biphalin Wound Dressing in Diabetic Mice: In Vitro and In Vivo Studies

M Rybka, Ł Mazurek, J Czuwara… - Journal of Natural …, 2024 - Taylor & Francis
Strategies for successful healing of diabetic wounds are lacking. Natural-derived dressings
have gained much attention due to their promising properties. We hypothesized that keratin …

Development of a novel keratin dressing which accelerates full-thickness skin wound healing in diabetic mice: In vitro and in vivo studies

M Konop, J Czuwara, E Kłodzińska… - Journal of …, 2018 - journals.sagepub.com
Impaired wound healing is a major medical problem in diabetes. The objective of this study
was to determine the possible application of an insoluble fraction of fur-derived keratin …

Keratin-Butyrate Scaffolds Promote Skin Wound Healing in Diabetic Rats through Down-Regulation of IL-1β and Up-Regulation of Keratins 16 and 17

M Konop, M Rybka, M Szudzik, Ł Mazurek… - Journal of Natural …, 2023 - Taylor & Francis
Impaired wound healing particularly in diabetics creates a significant healthcare burden.
The study aimed to evaluate the effect of keratin-butyrate fibers (FKDP+ 0.1% NaBu) in a full …

Keratin biomaterials in skin wound healing, an old player in modern medicine: a mini review

M Konop, M Rybka, A Drapała - Pharmaceutics, 2021 - mdpi.com
Impaired wound healing is a major medical problem. To solve it, researchers around the
world have turned their attention to the use of tissue-engineered products to aid in skin …

Engineered keratin/bFGF hydrogel to promote diabetic wound healing in rats

C Sun, Y Huang, L Wang, J Deng, R Qing, X Ge… - International Journal of …, 2024 - Elsevier
Keratin materials are promising in wound healing acceleration, however, it is a challenge for
the keratin to efficiently therapy the impaired wound healing, such as diabetic foot ulcers …

Keratin-based wound dressings: From waste to wealth

W Ye, M Qin, R Qiu, J Li - International Journal of Biological …, 2022 - Elsevier
Keratin is a natural protein with a high content of cysteine residues (7–13%) and is widely
found in hair, wool, horns, hooves, and nails. Keratin possesses abundant cell-binding …

Human keratin matrices promote wound healing by modulating skin cell expression of cytokines and growth factors

AN Ramey‐Ward, HP Walthall, S Smith… - Wound Repair and …, 2024 - Wiley Online Library
A wide variety of biomaterials has been developed to assist in wound healing, including
acellular animal and human‐derived protein matrices. However, millions of patients …

The role of allogenic keratin‐derived dressing in wound healing in a mouse model

M Konop, D Sulejczak, J Czuwara… - Wound Repair and …, 2017 - Wiley Online Library
Keratin is an interesting protein needed for wound healing and tissue recovery. We have
recently proposed a new, simple and inexpensive method to obtain fur and hair keratin …

Keratin scaffolds containing casomorphin stimulate macrophage infiltration and accelerate full-thickness cutaneous wound healing in diabetic mice

M Konop, AK Laskowska, M Rybka, E Kłodzińska… - Molecules, 2021 - mdpi.com
Impaired wound healing is a major medical challenge, especially in diabetics. Over the
centuries, the main goal of tissue engineering and regenerative medicine has been to invent …

Evaluation of keratin biomaterial containing silver nanoparticles as a potential wound dressing in full‐thickness skin wound model in diabetic mice

M Konop, J Czuwara, E Kłodzińska… - Journal of tissue …, 2020 - Wiley Online Library
Keratin is a cytoskeletal scaffolding protein essential for wound healing and tissue recovery.
The aim of the study was to evaluate the potential role of insoluble fur keratin‐derived …