Biofabrication strategies for creating microvascular complexity
Abstract Design and fabrication of effective biomimetic vasculatures constitutes a relevant
and yet unsolved challenge, lying at the heart of tissue repair and regeneration strategies …
and yet unsolved challenge, lying at the heart of tissue repair and regeneration strategies …
[HTML][HTML] Engineering the multiscale complexity of vascular networks
The survival of vertebrate organisms depends on highly regulated delivery of oxygen and
nutrients through vascular networks that pervade nearly all tissues in the body …
nutrients through vascular networks that pervade nearly all tissues in the body …
Microscale technologies for engineering complex tissue structures
Engineered tissue scaffolds aim to reproduce the body's architectural and geometrical
intricacies, including vital cell–cell interactions. These scaffolds serve as synthetic …
intricacies, including vital cell–cell interactions. These scaffolds serve as synthetic …
Engineering new microvascular networks on‐chip: ingredients, assembly, and best practices
JJ Tronolone, A Jain - Advanced functional materials, 2021 - Wiley Online Library
Tissue engineered grafts show great potential as regenerative implants for diseased or
injured tissues within the human body. However, these grafts suffer from poor nutrient …
injured tissues within the human body. However, these grafts suffer from poor nutrient …
Manufacturing the multiscale vascular hierarchy: progress toward solving the grand challenge of tissue engineering
In human vascular anatomy, blood flows from the heart to organs and tissues through a
hierarchical vascular tree, comprising large arteries that branch into arterioles and further …
hierarchical vascular tree, comprising large arteries that branch into arterioles and further …
From arteries to capillaries: approaches to engineering human vasculature
S Fleischer, DN Tavakol… - Advanced functional …, 2020 - Wiley Online Library
From microscaled capillaries to millimeter‐sized vessels, human vasculature spans multiple
scales and cell types. The convergence of bioengineering, materials science, and stem cell …
scales and cell types. The convergence of bioengineering, materials science, and stem cell …
Microfabricated biomaterials for engineering 3D tissues
Mimicking natural tissue structure is crucial for engineered tissues with intended
applications ranging from regenerative medicine to biorobotics. Native tissues are highly …
applications ranging from regenerative medicine to biorobotics. Native tissues are highly …
Microphysiological engineering of self-assembled and perfusable microvascular beds for the production of vascularized three-dimensional human microtissues
The vasculature is an essential component of the circulatory system that plays a vital role in
the development, homeostasis, and disease of various organs in the human body. The …
the development, homeostasis, and disease of various organs in the human body. The …
Engineering perfused microvascular networks into microphysiological systems platforms
JW Andrejecsk, CCW Hughes - Current Opinion in Biomedical Engineering, 2018 - Elsevier
The microvasculature is an essential component of nearly all tissues, with most cells
residing within 200 μm of a vessel. Endothelial cells form the inner wall of microvessels and …
residing within 200 μm of a vessel. Endothelial cells form the inner wall of microvessels and …
Engineering of functional, perfusable 3D microvascular networks on a chip
Generating perfusable 3D microvessels in vitro is an important goal for tissue engineering,
as well as for reliable modelling of blood vessel function. To date, in vitro blood vessel …
as well as for reliable modelling of blood vessel function. To date, in vitro blood vessel …