[HTML][HTML] Translation of preclinical PET imaging findings: Challenges and motion correction to overcome the confounding effect of anesthetics

A Miranda, D Bertoglio, S Stroobants, S Staelens… - Frontiers in …, 2021 - frontiersin.org
Preclinical brain positron emission tomography (PET) in animals is performed using
anesthesia to avoid movement during the PET scan. In contrast, brain PET scans in humans …

[HTML][HTML] Optimised motion tracking for positron emission tomography studies of brain function in awake rats

AZ Kyme, VW Zhou, SR Meikle, C Baldock, RR Fulton - PloS one, 2011 - journals.plos.org
Positron emission tomography (PET) is a non-invasive molecular imaging technique using
positron-emitting radioisotopes to study functional processes within the body. High …

Tracking and characterizing the head motion of unanaesthetized rats in positron emission tomography

A Kyme, S Meikle, C Baldock… - Journal of The Royal …, 2012 - royalsocietypublishing.org
Positron emission tomography (PET) is an important in vivo molecular imaging technique for
translational research. Imaging unanaesthetized rats using motion-compensated PET …

A motion adaptive animal chamber for PET imaging of freely moving animals

V Zhou, J Eisenhuth, A Kyme, M Akhtar… - … on Nuclear Science, 2013 - ieeexplore.ieee.org
Small animal positron emission tomography (PET) is a powerful method for studying the
molecular origins of debilitating brain disorders such as dementia, depression and …

[HTML][HTML] PET imaging of freely moving interacting rats

A Miranda, MS Kang, S Blinder, R Bouhachi, JP Soucy… - Neuroimage, 2019 - Elsevier
Awake rat brain positron emission tomography (PET) has previously been developed to
avoid the influence of anesthesia on the rat brain response. In the present work, we further …

Optimising rigid motion compensation for small animal brain PET imaging

MG Spangler-Bickell, L Zhou, AZ Kyme… - Physics in Medicine …, 2016 - iopscience.iop.org
Motion compensation (MC) in PET brain imaging of awake small animals is attracting
increased attention in preclinical studies since it avoids the confounding effects of …

Feasibility of template-guided attenuation correction in cat brain PET imaging

JS Kim, JS Lee, MH Park, KM Kim, SH Oh… - Molecular imaging and …, 2010 - Springer
Purpose Attenuation correction (AC) is important in quantitative positron emission
tomography (PET) imaging of medium-sized animals such as the cat. However, additional …

Markerless rat head motion tracking using structured light for brain PET imaging of unrestrained awake small animals

A Miranda, S Staelens, S Stroobants… - Physics in Medicine & …, 2017 - iopscience.iop.org
Preclinical positron emission tomography (PET) imaging in small animals is generally
performed under anesthesia to immobilize the animal during scanning. More recently, for rat …

Detecting and estimating head motion in brain PET acquisitions using raw time-of-flight PET data

PJ Schleyer, JT Dunn, S Reeves… - Physics in Medicine …, 2015 - iopscience.iop.org
Head motion during brain PET imaging is not uncommon and can negatively affect image
quality. Motion correction techniques typically either use hardware to prospectively measure …

Evaluation of frame-based and event-by-event motion-correction methods for awake monkey brain PET imaging

X Jin, T Mulnix, CM Sandiego… - Journal of Nuclear …, 2014 - Soc Nuclear Med
PET imaging of nonhuman primates (NHPs) requires correction of head motion if the
subjects are scanned awake and their heads are unrestrained, because the NHPs move …