Precision medicine is a new frontier in healthcare that uses scientific methods to customize
medical treatment to the individual genes, anatomy, physiology, and lifestyle of each person …

The heart is not only our most vital, but also our most complex organ: Precisely controlled by
the interplay of electrical and mechanical fields, it consists of four chambers and four valves …

Recent progress in machine learning (ML), together with advanced computational power,
have provided new research opportunities in cardiovascular modeling. While classifying …

The treatment of individual patients in cardiology practice increasingly relies on advanced
imaging, genetic screening and devices. As the amount of imaging and other diagnostic …

Patient-specific computer models have been developed representing a variety of aspects of
the cardiovascular system spanning the disciplines of electrophysiology, electromechanics …

Mathematical models of the human heart are evolving to become a cornerstone of precision
medicine and support clinical decision making by providing a powerful tool to understand …

In vitro cardiac modeling has taken great strides in the past decade. While most cell and
engineered tissue models have focused on cell and tissue contractile function as readouts …

Cardiac anatomy plays a crucial role in determining cardiac function. However, there is a
poor understanding of how specific and localised anatomical changes affect different …

Advances in numerical methods and three-dimensional imaging techniques have enabled
the quantification of cardiovascular mechanics in subject-specific anatomic and physiologic …

The promise of cardiac tissue engineering is in the ability to recapitulate in vitro the
functional aspects of a healthy heart and disease pathology as well as to design …