Novel antibiotics for multidrug-resistant gram-positive microorganisms

D Koulenti, E Xu, I Yin Sum Mok, A Song… - Microorganisms, 2019 - mdpi.com
Increasing multidrug-resistance to Gram-positive pathogens, particularly to staphylococci,
enterococci and streptococci, is a major problem, resulting in significant morbidity, mortality …

Emerging treatment options for multi-drug-resistant bacterial infections

R Giurazza, MC Mazza, R Andini, P Sansone, MC Pace… - Life, 2021 - mdpi.com
Antimicrobial resistance (AMR) remains one of the top public health issues of global
concern. Among the most important strategies for AMR control there is the correct and …

Recently approved antibacterials for methicillin-resistant Staphylococcus aureus (MRSA) and other Gram-positive pathogens: the shock of the new

MZ David, M Dryden, T Gottlieb, P Tattevin… - International journal of …, 2017 - Elsevier
A number of novel antimicrobial drugs with activity against Gram-positive bacterial
pathogens have been licensed in the past 4 years. These drugs have the potential to enrich …

[HTML][HTML] Forthcoming therapeutic perspectives for infections due to multidrug-resistant Gram-positive pathogens

G Cornaglia, GM Rossolini - Clinical Microbiology and infection, 2009 - Elsevier
Multidrug resistance in Gram-positive pathogens emerged as a major therapeutic challenge
over two decades ago. The worldwide spread of methicillin-resistant Staphylococcus aureus …

Current and prospective treatments for multidrug-resistant gram-positive infections

JM Rybak, KE Barber, MJ Rybak - Expert opinion on …, 2013 - Taylor & Francis
Introduction: Staphylococcus aureus and Enterococcus spp. are two of the most common
organisms causing nosocomial infections today; and are consistently associated with high …

Novel antimicrobial agents for gram-negative pathogens

M Karvouniaris, MP Almyroudi, MH Abdul-Aziz, S Blot… - Antibiotics, 2023 - mdpi.com
Gram-negative bacterial resistance to antimicrobials has had an exponential increase at a
global level during the last decades and represent an everyday challenge, especially for the …

[HTML][HTML] New and improved? A review of novel antibiotics for Gram-positive bacteria

M Abbas, M Paul, A Huttner - Clinical Microbiology and Infection, 2017 - Elsevier
Background The number of antibiotics in the pipeline targeting Gram-positive pathogens has
increased in recent years. Aims This narrative review aims to provide a summary of existing …

Has the era of untreatable infections arrived?

DM Livermore - Journal of Antimicrobial Chemotherapy, 2009 - academic.oup.com
Antibiotic resistance is a major public health concern, with fears expressed that we shortly
will run out of antibiotics. In reality, the picture is more mixed, improving against some …

Advances in novel antibiotics to treat multidrug-resistant gram-negative bacterial infections

A Matlock, JA Garcia, K Moussavi, B Long… - Internal and Emergency …, 2021 - Springer
Antimicrobial resistance is a growing threat to public health and an increasingly common
problem for acute care physicians to confront. Several novel antibiotics have been approved …

Novel antibacterial agents for the treatment of serious Gram-positive infections

D Abbanat, M Macielag, K Bush - Expert Opinion on Investigational …, 2003 - Taylor & Francis
With the continuing development of clinical drug resistance among bacteria and the advent
of resistance to the recently released agents quinupristin-dalfopristin and linezolid, the need …