[HTML][HTML] Anti-trypanosomatid drug discovery: progress and challenges
Leishmaniasis (visceral and cutaneous), Chagas disease and human African
trypanosomiasis cause substantial death and morbidity, particularly in low-and middle …
trypanosomiasis cause substantial death and morbidity, particularly in low-and middle …
[HTML][HTML] Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need
The WHO recognizes human African trypanosomiasis, Chagas disease and the
leishmaniases as neglected tropical diseases. These diseases are caused by parasitic …
leishmaniases as neglected tropical diseases. These diseases are caused by parasitic …
[HTML][HTML] Of drugs and trypanosomatids: new tools and knowledge to reduce bottlenecks in drug discovery
A Bhattacharya, A Corbeil, RL do Monte-Neto… - Genes, 2020 - mdpi.com
Leishmaniasis (Leishmania species), sleeping sickness (Trypanosoma brucei), and Chagas
disease (Trypanosoma cruzi) are devastating and globally spread diseases caused by …
disease (Trypanosoma cruzi) are devastating and globally spread diseases caused by …
The current drug discovery landscape for trypanosomiasis and leishmaniasis: Challenges and strategies to identify drug targets
F Altamura, R Rajesh, CMC Catta‐Preta… - Drug development …, 2022 - Wiley Online Library
Human trypanosomiasis and leishmaniasis are vector‐borne neglected tropical diseases
caused by infection with the protozoan parasites Trypanosoma spp. and Leishmania spp …
caused by infection with the protozoan parasites Trypanosoma spp. and Leishmania spp …
Trypanocidal drugs: mechanisms, resistance and new targets
SR Wilkinson, JM Kelly - Expert reviews in molecular medicine, 2009 - cambridge.org
The protozoan parasites Trypanosoma brucei and Trypanosoma cruzi are the causative
agents of African trypanosomiasis and Chagas disease, respectively. These are debilitating …
agents of African trypanosomiasis and Chagas disease, respectively. These are debilitating …
[HTML][HTML] Challenges in Chagas disease drug development
AF Francisco, S Jayawardhana, F Olmo, MD Lewis… - Molecules, 2020 - mdpi.com
The protozoan parasite Trypanosoma cruzi causes Chagas disease, an important public
health problem throughout Latin America. Current therapeutic options are characterised by …
health problem throughout Latin America. Current therapeutic options are characterised by …
[HTML][HTML] An overview on target-based drug design against kinetoplastid protozoan infections: Human African trypanosomiasis, Chagas disease and leishmaniases
V Kourbeli, E Chontzopoulou, K Moschovou, D Pavlos… - Molecules, 2021 - mdpi.com
The protozoan diseases Human African Trypanosomiasis (HAT), Chagas disease (CD), and
leishmaniases span worldwide and therefore their impact is a universal concern. The …
leishmaniases span worldwide and therefore their impact is a universal concern. The …
Trypanosomatid parasites causing neglected diseases
K Nussbaum, J Honek, CC Cadmus… - Current medicinal …, 2010 - ingentaconnect.com
Parasitic diseases such as Kala azar (visceral leishmaniasis), Chagas disease (American
trypanosomiasis) and African sleeping sickness (human African trypanosomiasis) are …
trypanosomiasis) and African sleeping sickness (human African trypanosomiasis) are …
[HTML][HTML] Challenges in drug discovery targeting TriTryp diseases with an emphasis on leishmaniasis
LM Alcântara, TCS Ferreira, FR Gadelha… - International Journal for …, 2018 - Elsevier
Tritryps diseases are devastating parasitic neglected infections caused by Leishmania spp.,
Trypanosoma cruzi and Trypanosoma brucei subspecies. Together, these parasites affect …
Trypanosoma cruzi and Trypanosoma brucei subspecies. Together, these parasites affect …
[HTML][HTML] Drug discovery for chagas disease: A viewpoint
JM Kratz - Acta tropica, 2019 - Elsevier
Chagas disease is a neglected tropical disease caused by the protozoan parasite
Trypanosoma cruzi. It is a significant public health problem, affecting millions of people …
Trypanosoma cruzi. It is a significant public health problem, affecting millions of people …