Synthesis and antiviral activity of new substituted pyrimidine glycosides

MMM Ramiz, WA El‐Sayed, E Hagag… - Journal of …, 2011 - Wiley Online Library
A number of N‐substituted pyrimidine glycosides were synthesized by coupling reaction of
the pyrimidine base with acetobromosugars followed by deprotection. The synthesized …

Synthesis and antiviral screening of some novel pyridazine and triazolopyridazine nucleosides

AE Rashad, AH Shamroukh, MA Ali… - … Journal of Main …, 2007 - Wiley Online Library
Some novel cyclic and acyclic pyridazine and triazolopyridazine nucleoside derivatives
were prepared. Some of the prepared products were selected and tested for antiviral activity …

Antiviral activity of pyrimidine containing compounds: Patent review

TA Farghaly, MF Harras, AMR Alsaedi… - Mini Reviews in …, 2023 - ingentaconnect.com
Viruses are still the most prevalent infectious pathogens on a worldwide scale, with many of
them causing life-threatening illnesses in humans. Influenza viruses, because of their …

Synthesis and antiviral evaluation of some new pyrazole and fused pyrazolopyrimidine derivatives

AE Rashad, MI Hegab, RE Abdel-Megeid… - Bioorganic & medicinal …, 2008 - Elsevier
Some novel substituted pyrazole and pyrazolo [3, 4-d] pyrimidine derivatives 2, 4, 8, and 9
were synthesized. Also, some acyclic S-nucleosides of pyrazolo [3, 4-d] pyrimidine …

Synthesis of novel pyrimidine and fused pyrimidine derivatives

MR Mahmoud, AK El-Ziaty, MF Ismail… - European Journal of …, 2011 - eurjchem.com
Amino-2-(benzylthio)-6-(4-methoxyphenyl) pyrimidine-5-carbonitrile (1) was prepared by
treatment of s-benzylthiuronium chloride with 2-(4-methoxybenzylidene) malononitrile in …

Synthesis and anti-influenza virus activity of novel pyrimidine derivatives

M Hisaki, H Imabori, M Azuma, T Suzutani, F Iwakura… - Antiviral research, 1999 - Elsevier
Efficient synthetic routes of 2-amino-4-(ω-hydroxyalkylamino) pyrimidine derivatives were
investigated in relation to the anti-influenza virus activity of these compounds. The …

Synthesis, anti-HIV activity and molecular modeling study of some new pyrimidine analogues

YA Marich, NJ Al-Salihi… - European Journal of …, 2014 - eurjchem.com
Abstract A new series of 2, 6-diamino-5-arylazo-4-chloropyrimidine analogues (6-13) were
synthesized from the pyrimidine scaffold 5, via diazotization with various amines …

Synthesis of guanidinopyrimidine derivatives and their biological activities

Y Shuto, E Taniguchi, K Maekawa - 1974 - catalog.lib.kyushu-u.ac.jp
Present paper deals with the synthesis of guanidinopyrimidine derivatives from substituted-
biguanides, and with thier biological activities. 2-Arylguanidino-4, 6-dimethylpyrimidine …

A review on synthesis, anticancer and antiviral potentials of pyrimidine derivatives

S Kumar, A Deep, B Narasimhan - Current Bioactive …, 2019 - ingentaconnect.com
Background: Pyrimidine is the six membered heterocyclic aromatic compound similar to
benzene and pyridine containing two nitrogen atoms at 1st and 3rd positions. Pyrimidine is …

Synthesis, pharmacological and biological screening of some novel pyrimidine derivatives

K Ishwar Bhat, A Kumar, M Nisar, P Kumar - Medicinal Chemistry …, 2014 - Springer
In the present study a new series of 4-substituted phenyl-6-(pyridin-2-yl) pyrimidin-2-ol (1–9)
and 4-substituted phenyl-6-(pyridin-2-yl) pyrimidin-2-thiol (10–18) have been synthesized by …