Synthetic gene drive (GD) systems constitute a form of novel invasive environmental
biotechnology with far-reaching consequences beyond those of other known genetically …

Gene drive technology, in which fast‐spreading engineered drive alleles are introduced into
wild populations, represents a promising new tool in the fight against vector‐borne diseases …

Gene drive organisms are a recent development created by using methods of genetic
engineering; they inherit genetic constructs that are passed on to future generations with a …

Robust methods of predicting how gene drive systems will interact with ecosystems is
essential for safe deployment of gene drive technology. We describe how quantitative tools …

Risk assessors, risk managers, developers, potential applicants, and other stakeholders at
many levels discuss the need for new or further risk assessment guidance for deliberate …

Potential future application of engineered gene drives (GDs), which bias their own
inheritance and can spread genetic modifications in wild target populations, has sparked …

Compared to previous releases of genetically modified organisms (GMOs) which were
primarily plants, gene drives represent a paradigm shift in the handling of GMOs: Current …

The ability to engineer gene drives (genetic elements that bias their own inheritance) has
sparked enthusiasm and concerns. Engineered gene drives could potentially be used to …

Gene drive organisms (GDOs) have been suggested as approaches to combat some of the
most pressing environmental and public health issues. No such organisms have so far been …

Advances in molecular and synthetic biology are enabling the engineering of gene drives in
insects for disease vector/pest control. Engineered gene drives (that bias their own …