Serum bilirubin levels in overweight and obese individuals: the importance of anti-inflammatory and antioxidant responses
L Žiberna, Z Jenko-Pražnikar, A Petelin - Antioxidants, 2021 - mdpi.com
Obesity is a chronic condition involving low-grade inflammation and increased oxidative
stress; thus, obese and overweight people have lower values of serum bilirubin. Essentially …
stress; thus, obese and overweight people have lower values of serum bilirubin. Essentially …
Bilirubin reduces visceral obesity and insulin resistance by suppression of inflammatory cytokines
R Takei, T Inoue, N Sonoda, M Kohjima, M Okamoto… - PloS one, 2019 - journals.plos.org
Objective Although previous studies have reported a negative relationship between serum
bilirubin concentration and the development of diabetes mellitus (DM), the relationship …
bilirubin concentration and the development of diabetes mellitus (DM), the relationship …
The physiology of bilirubin: health and disease equilibrium
L Vitek, TD Hinds, DE Stec, C Tiribelli - Trends in molecular medicine, 2023 - cell.com
Bilirubin has several physiological functions, both beneficial and harmful. In addition to
reactive oxygen species-scavenging activities, bilirubin has potent immunosuppressive …
reactive oxygen species-scavenging activities, bilirubin has potent immunosuppressive …
Serum bilirubin correlates with serum adipokines in normal weight and overweight asymptomatic adults
A Petelin, M Jurdana, Z Jenko Pražnikar… - Acta Clinica …, 2020 - hrcak.srce.hr
Sažetak Overweight and obesity are considered as chronic low-grade inflammation
accompanied by imbalanced production of adipokines. The aim of this study was to …
accompanied by imbalanced production of adipokines. The aim of this study was to …
The role of bilirubin in diabetes, metabolic syndrome, and cardiovascular diseases
L Vítek - Frontiers in pharmacology, 2012 - frontiersin.org
Bilirubin belongs to a phylogenetically old superfamily of tetrapyrrolic compounds, which
have multiple biological functions. Although for decades bilirubin was believed to be only a …
have multiple biological functions. Although for decades bilirubin was believed to be only a …
Bilirubin increases insulin sensitivity by regulating cholesterol metabolism, adipokines and PPARγ levels
J Liu, H Dong, Y Zhang, M Cao, L Song, Q Pan… - Scientific reports, 2015 - nature.com
Obesity can cause insulin resistance and type 2 diabetes. Moderate elevations in bilirubin
levels have anti-diabetic effects. This study is aimed at determining the mechanisms by …
levels have anti-diabetic effects. This study is aimed at determining the mechanisms by …
Serum bilirubin level is increased in metabolically healthy obesity
J Fu, Q Wang, L Zhang, J Liu, G Wang - Frontiers in Endocrinology, 2022 - frontiersin.org
Objectives Bilirubin is a biochemical substance with metabolic benefits. The objective of this
research was to elucidate the association between serum bilirubin levels and metabolic …
research was to elucidate the association between serum bilirubin levels and metabolic …
Bilirubin in metabolic syndrome and associated inflammatory diseases: new perspectives
P Novák, AO Jackson, GJ Zhao, K Yin - Life Sciences, 2020 - Elsevier
Diabetes mellitus is one of the major global health issues, which is closely related to
metabolic dysfunction and the chronic inflammatory diseases. Multiple studies have …
metabolic dysfunction and the chronic inflammatory diseases. Multiple studies have …
Effects of serum bilirubin on atherosclerotic processes
SJ Kang, C Lee, P Kruzliak - Annals of medicine, 2014 - Taylor & Francis
This review highlights the protective roles of bilirubin against the atherosclerotic process.
Bilirubin belongs to the superfamily of tetrapyrrolic compounds formed during heme …
Bilirubin belongs to the superfamily of tetrapyrrolic compounds formed during heme …
Bilirubin is independently associated with oxidized LDL levels in young obese patients
H Nascimento, AI Alves, S Coimbra, C Catarino… - Diabetology & metabolic …, 2015 - Springer
Background Bilirubin can prevent lipid oxidation in vitro, but the association in vivo with
oxidized low-density lipoprotein (Ox-LDL) levels has been poorly explored. Our aim is to the …
oxidized low-density lipoprotein (Ox-LDL) levels has been poorly explored. Our aim is to the …