[HTML][HTML] Sensitization of TRPV1 by protein kinase C in rats with mono-iodoacetate-induced joint pain
K Koda, K Hyakkoku, K Ogawa, K Takasu, S Imai… - Osteoarthritis and …, 2016 - Elsevier
Objective To assess the functional changes of Transient receptor potential vanilloid 1
(TRPV1) receptor and to clarify its mechanism in a rat mono-iodoacetate (MIA)-induced joint …
(TRPV1) receptor and to clarify its mechanism in a rat mono-iodoacetate (MIA)-induced joint …
[HTML][HTML] Suppression of joint pain in transient receptor potential vanilloid 4 knockout rats with monoiodoacetate-induced osteoarthritis
M Soga, T Izumi, I Nanchi, N Horita, M Yamamoto… - Pain …, 2021 - journals.lww.com
Methods: We developed TRPV4-knockout (TRPV4-KO) rats and assessed the effects of
Trpv4 gene deficiency in a monoiodoacetate (MIA)-induced OA pain model (MIA rats) by …
Trpv4 gene deficiency in a monoiodoacetate (MIA)-induced OA pain model (MIA rats) by …
Sensitization of transient receptor potential vanilloid 4 and increasing its endogenous ligand 5, 6-epoxyeicosatrienoic acid in rats with monoiodoacetate-induced …
M Hinata, S Imai, T Sanaki, J Tsuchida, T Yoshioka… - Pain, 2018 - journals.lww.com
Transient receptor potential vanilloid 4 (TRPV4) receptor modulates pain, and this has been
noted in several animal models. However, the involvement of TRPV4 in osteoarthritic (OA) …
noted in several animal models. However, the involvement of TRPV4 in osteoarthritic (OA) …
Attenuation of experimental arthritis in TRPV1R knockout mice
NJ Barton, DS McQueen, D Thomson… - … and molecular pathology, 2006 - Elsevier
The Transient Receptor Potential Vanilloid 1 (TRPV1R) is a ligand-gated, non-selective
cation channel expressed predominantly by sensory neurons. TRPV1Rs respond to a …
cation channel expressed predominantly by sensory neurons. TRPV1Rs respond to a …
[HTML][HTML] Vanilloid receptor TRPV1-mediated phosphorylation of ERK in murine adjuvant arthritis
Y Chen, HH Willcockson, JG Valtschanoff - Osteoarthritis and cartilage, 2009 - Elsevier
OBJECTIVE: The vanilloid receptor transient receptor potential vanilloid 1 (TRPV1),
expressed by sensory neurons that innervate joints, is implicated in arthritis but the …
expressed by sensory neurons that innervate joints, is implicated in arthritis but the …
Role of transient receptor potential vanilloid 1 receptors in adjuvant-induced chronic arthritis: in vivo study using gene-deficient mice
A Szabo, Z Helyes, K Sandor, A Bite, E Pinter… - … of Pharmacology and …, 2005 - ASPET
The transient receptor potential vanilloid 1 (TRPV1) receptor is a nonselective cation
channel localized on a subset of primary sensory neurons and can be activated by a wide …
channel localized on a subset of primary sensory neurons and can be activated by a wide …
Role of transient receptor potential vanilloid 4 in rat joint inflammation
A Denadai‐Souza, L Martin, MAV de Paula… - Arthritis & …, 2012 - Wiley Online Library
Objective To determine whether activation of transient receptor potential vanilloid 4 (TRPV‐
4) induces inflammation in the rat temporomandibular joint (TMJ), and to assess the effects …
4) induces inflammation in the rat temporomandibular joint (TMJ), and to assess the effects …
Capsaicin-induced vasoconstriction in the mouse knee joint: a study using TRPV1 knockout mice
Capsaicin is the pungent component of chilli peppers that concomitantly activates and
desensitizes C-fibre and Aδ sensory nerve fibres. Stimulation causes an acute neurogenic …
desensitizes C-fibre and Aδ sensory nerve fibres. Stimulation causes an acute neurogenic …
Expression of transient receptor potential vanilloid 1 (TRPV1) in synovial fibroblasts from patients with osteoarthritis and rheumatoid arthritis
A Engler, A Aeschlimann, BR Simmen… - Biochemical and …, 2007 - Elsevier
The transient receptor potential vanilloid 1 (TRPV1) is a nonselective cation channel, which
is mainly expressed by nociceptive neurons in dorsal root and trigeminal ganglia. However …
is mainly expressed by nociceptive neurons in dorsal root and trigeminal ganglia. However …
Involvement of transient receptor potential vanilloid 1 in the vascular and hyperalgesic components of joint inflammation
Objective To investigate the endogenous involvement of transient receptor potential
vanilloid 1 (TRPV1) in a model of knee joint inflammation in the mouse. Methods Following …
vanilloid 1 (TRPV1) in a model of knee joint inflammation in the mouse. Methods Following …