Alpha-synuclein (αSyn) protein levels correlate with the risk and severity of Parkinson's
disease and related neurodegenerative diseases. Lowering αSyn is being actively …

Abstract α-synuclein (α-SYN) is a major pathologic contributor to Parkinson's disease (PD).
Multiplication of α-SYN encoding gene (SNCA) is correlated with early onset of the disease …

Synucleinopathies are a group of neurodegenerative diseases that share a common
pathological lesion of intracellular protein inclusions largely composed by aggregates of …

Parkinson's disease (PD) is the second most common neurodegenerative disorder
characterized by the accumulation of protein aggregates (namely Lewy bodies) in …

Epigenetic deregulation of α‐synuclein plays a key role in Parkinson's disease (PD).
Analysis of the SNCA promoter using the ENCODE database revealed the presence of …

Parkinson's disease (PD) is one of the most common neurodegenerative diseases, but no
disease modifying therapies have been successful in clinical translation presenting a major …

Background Alpha synuclein (SNCA) has been linked to neurodegenerative diseases
(synucleinopathies) that include Parkinson's disease (PD). Although the primary …

Parkinson's disease (PD) is a prevalent neurodegenerative disease with no approved
disease-modifying therapies. Multiplications, mutations, and single nucleotide …

α-Synuclein (asyn) is a key pathogenetic factor in a group of neurodegenerative diseases
generically known as synucleinopathies, including Parkinson's disease (PD), dementia with …

Accumulation of α-Synuclein (α-Syn) causes Parkinson's disease (PD) as well as other
synucleopathies. α-Syn is the major component of Lewy bodies and Lewy neurites, the …