[HTML][HTML] Learning from prepandemic data to forecast viral escape

NN Thadani, S Gurev, P Notin, N Youssef, NJ Rollins… - Nature, 2023 - nature.com
Effective pandemic preparedness relies on anticipating viral mutations that are able to
evade host immune responses to facilitate vaccine and therapeutic design. However, current …

[HTML][HTML] Understanding protection from SARS-CoV-2 by studying reinfection

J Overbaugh - Nature Medicine, 2020 - nature.com
Understanding protection from SARS-CoV-2 by studying reinfection | Nature Medicine Skip to
main content Thank you for visiting nature.com. You are using a browser version with limited …

SARS-CoV-2 within-host diversity and transmission

KA Lythgoe, M Hall, L Ferretti, M de Cesare… - Science, 2021 - science.org
INTRODUCTION Genome sequencing at an unprecedented scale during the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is helping to track spread of …

[HTML][HTML] An early warning system for emerging SARS-CoV-2 variants

L Subissi, A von Gottberg, L Thukral, N Worp… - Nature medicine, 2022 - nature.com
An early warning system for emerging SARS-CoV-2 variants | Nature Medicine Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

An antibody-escape estimator for mutations to the SARS-CoV-2 receptor-binding domain

AJ Greaney, TN Starr, JD Bloom - Virus evolution, 2022 - academic.oup.com
A key goal of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) surveillance
is to rapidly identify viral variants with mutations that reduce neutralization by polyclonal …

[HTML][HTML] Reconstruction of the full transmission dynamics of COVID-19 in Wuhan

X Hao, S Cheng, D Wu, T Wu, X Lin, C Wang - Nature, 2020 - nature.com
As countries in the world review interventions for containing the pandemic of coronavirus
disease 2019 (COVID-19), important lessons can be drawn from the study of the full …

[HTML][HTML] Deep mutational learning predicts ACE2 binding and antibody escape to combinatorial mutations in the SARS-CoV-2 receptor-binding domain

JM Taft, CR Weber, B Gao, RA Ehling, J Han, L Frei… - Cell, 2022 - cell.com
The continual evolution of SARS-CoV-2 and the emergence of variants that show resistance
to vaccines and neutralizing antibodies threaten to prolong the COVID-19 pandemic …

[HTML][HTML] Untangling introductions and persistence in COVID-19 resurgence in Europe

P Lemey, N Ruktanonchai, SL Hong, V Colizza… - Nature, 2021 - nature.com
After the first wave of SARS-CoV-2 infections in spring 2020, Europe experienced a
resurgence of the virus starting in late summer 2020 that was deadlier and more difficult to …

[HTML][HTML] Defining the risk of SARS-CoV-2 variants on immune protection

MM DeGrace, E Ghedin, MB Frieman, F Krammer… - Nature, 2022 - nature.com
The global emergence of many severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) variants jeopardizes the protective antiviral immunity induced after infection or …

Predicting the mutational drivers of future SARS-CoV-2 variants of concern

MC Maher, I Bartha, S Weaver, J Di Iulio… - Science translational …, 2022 - science.org
SARS-CoV-2 evolution threatens vaccine-and natural infection–derived immunity and the
efficacy of therapeutic antibodies. To improve public health preparedness, we sought to …