Comprehensive review of targeted therapy for colorectal cancer

YH Xie, YX Chen, JY Fang - Signal transduction and targeted therapy, 2020 - nature.com
Colorectal cancer (CRC) is among the most lethal and prevalent malignancies in the world
and was responsible for nearly 881,000 cancer-related deaths in 2018. Surgery and …

Current targeted therapy for metastatic colorectal cancer

T Ohishi, MK Kaneko, Y Yoshida, A Takashima… - International journal of …, 2023 - mdpi.com
Colorectal cancer (CRC) is the third most common type of cancer and the second leading
cause of cancer deaths worldwide. Surgery or surgery plus radiotherapy and/or …

Current targeted therapies in the treatment of advanced colorectal cancer: a review

A Moriarity, J O'Sullivan, J Kennedy… - … in medical oncology, 2016 - journals.sagepub.com
Treatment strategies for metastatic colorectal cancer (mCRC) patients have undergone
dramatic changes in the past decade and despite improved patient outcomes, there still exist …

Colorectal cancer: from genetic landscape to targeted therapy

M El Bali, J Bakkach, M Bennani Mechita - Journal of Oncology, 2021 - Wiley Online Library
Colorectal cancer (CRC) is the third most common cancer type and the second cause of
death worldwide. The advancement in understanding molecular pathways involved in CRC …

Current progress in targeted therapy for colorectal cancer

J Ortega, CE Vigil, C Chodkiewicz - Cancer control, 2010 - journals.sagepub.com
Background: Several molecular targeting agents are available and being used in patients
with colorectal cancer, and many others are being tested clinically. Methods: The authors …

[HTML][HTML] Molecular mechanisms targeting drug-resistance and metastasis in colorectal cancer: Updates and beyond

S Al Bitar, M El-Sabban, S Doughan… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most diagnosed malignancy and a major leading cause
of cancer-related deaths worldwide. Despite advances in therapeutic regimens, the number …

Molecular targeted drugs and treatment of colorectal cancer: recent progress and future perspectives

F Geng, Z Wang, H Yin, J Yu, B Cao - Cancer biotherapy & …, 2017 - liebertpub.com
Nowadays, colorectal cancer is the fourth most common type of tumor all over the world.
When diagnosed,∼ 50%–60% of tumors have metastasized, thus resulting in a grim …

[HTML][HTML] Current and emerging therapeutic approaches for colorectal cancer: A comprehensive review

A Kumar, V Gautam, A Sandhu, K Rawat… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) affects 1 in 23 males and 1 in 25 females, making it the third most
common cancer. With roughly 608000 deaths worldwide, CRC accounts for 8% of all cancer …

Role of targeted agents in metastatic colorectal cancer

H Prenen, L Vecchione, E Van Cutsem - Targeted oncology, 2013 - Springer
Despite a decrease in incidence and mortality, colorectal cancer (CRC) still represents the
second leading cause of cancer worldwide. Recurrence following surgery and adjuvant …

[HTML][HTML] Molecularly targeted therapy for metastatic colon cancer: proven treatments and promising new agents

M El Zouhairi, A Charabaty… - … cancer research: GCR, 2011 - ncbi.nlm.nih.gov
Treatment algorithms and survival for patients with metastatic colorectal cancer have
changed dramatically over the past decade, largely due to the advent of molecularly …