Function and evolution of vertebrate globins

T Burmester, T Hankeln - Acta Physiologica, 2014 - Wiley Online Library
Globins are haem‐proteins that bind O2 and thus play an important role in the animal's
respiration and oxidative energy production. However, globins may also have other …

Neuroglobin and cytoglobin: genes, proteins and evolution

T Burmester, M Haberkamp, S Mitz, A Roesner… - IUBMB …, 2004 - Wiley Online Library
Hemoglobin and myoglobin are oxygen transport and storage proteins of most vertebrates.
Neuroglobin (Ngb) and cytoglobin (Cygb)‐two recent additions to the vertebrate globin …

[HTML][HTML] Lessons from the post-genomic era: Globin diversity beyond oxygen binding and transport

A Keppner, D Maric, M Correia, TW Koay, IMC Orlando… - Redox biology, 2020 - Elsevier
Vertebrate hemoglobin (Hb) and myoglobin (Mb) were among the first proteins whose
structures and sequences were determined over 50 years ago. In the subsequent …

[HTML][HTML] Neuroglobin and cytoglobin

A Pesce, M Bolognesi, A Bocedi, P Ascenzi… - EMBO …, 2002 - embopress.org
Neuroglobin and cytoglobin are two recently discovered members of the vertebrate globin
family. Both are intracellular proteins endowed with hexacoordinated heme‐Fe atoms, in …

A globin gene of ancient evolutionary origin in lower vertebrates: evidence for two distinct globin families in animals

A Roesner, C Fuchs, T Hankeln… - Molecular Biology and …, 2005 - academic.oup.com
Hemoglobin, myoglobin, neuroglobin, and cytoglobin are four types of vertebrate globins
with distinct tissue distributions and functions. Here, we report the identification of a fifth and …

Cytoglobin: A Novel Globin Type Ubiquitously Expressed inVertebrate Tissues

T Burmester, B Ebner, B Weich… - Molecular biology and …, 2002 - academic.oup.com
Vertebrates possess multiple respiratory globins that differ in terms of structure, function, and
tissue distribution. Three types of globins have been described so far: hemoglobin facilitates …

Globin X is a six-coordinate globin that reduces nitrite to nitric oxide in fish red blood cells

P Corti, J Xue, J Tejero, N Wajih… - Proceedings of the …, 2016 - National Acad Sciences
The discovery of novel globins in diverse organisms has stimulated intense interest in their
evolved function, beyond oxygen binding. Globin X (GbX) is a protein found in fish …

Functional properties of neuroglobin and cytoglobin. Insights into the ancestral physiological roles of globins

A Fago, C Hundahl, H Malte, RE Weber - IUBMB life, 2004 - Wiley Online Library
Neuroglobin and cytoglobin are two recently discovered vertebrate globins, which are
expressed at low levels in neuronal tissues and in all tissues investigated so far …

What is the function of neuroglobin?

T Burmester, T Hankeln - Journal of Experimental Biology, 2009 - journals.biologists.com
For a long time, haemoglobin and myoglobin had been assumed to represent the only
globin types of vertebrates. In 2000, however, we discovered a third globin type by mining …

Androglobin: a chimeric globin in metazoans that is preferentially expressed in mammalian testes

D Hoogewijs, B Ebner, F Germani… - Molecular biology …, 2012 - academic.oup.com
Comparative genomic studies have led to the recent identification of several novel globin
types in the Metazoa. They have revealed a surprising evolutionary diversity of functions …