Lack of dystrophin causes muscle degeneration, which is exacerbated by chronic
inflammation and reduced regenerative capacity of muscle stem cells in Duchenne Muscular …

Immunological and inflammatory processes downstream of dystrophin deficiency as well as
metabolic abnormalities, defective autophagy, and loss of regenerative capacity all …

Duchenne muscular dystrophy (DMD) is a lethal, X-linked neuromuscular disorder caused
by the absence of dystrophin protein, which is essential for muscle fiber integrity. Loss of …

Duchenne muscular dystrophy (DMD) is a genetic disease characterised by skeletal muscle
degeneration and progressive muscle wasting, which is caused by loss-of-function …

Duchenne muscular dystrophy (DMD) is a severe and progressive, X-linked, neuromuscular
disorder caused by mutations in the dystrophin gene. In DMD, the lack of functional …

Duchenne muscular dystrophy (DMD), an incurable and a progressive muscle wasting
disease, is caused by the absence of dystrophin protein, leading to recurrent muscle fiber …

Duchenne muscular dystrophy is a lethal muscle-wasting disease that affects boys.
Mutations in the dystrophin gene result in the absence of the dystrophin glycoprotein …

Fibrosis is the aberrant deposition of extracellular matrix (ECM) components during tissue
healing leading to loss of its architecture and function. Fibrotic diseases are often associated …

Absence of dystrophin makes skeletal muscle more susceptible to injury, resulting in
breaches of the plasma membrane and chronic inflammation in Duchenne muscular …

Duchenne muscular dystrophy (DMD) is a severe, progressive, muscle-wasting disease,
characterized by progressive deterioration of skeletal muscle that causes rapid loss of …