[HTML][HTML] Role of testosterone in SARS-CoV-2 infection: A key pathogenic factor and a biomarker for severe pneumonia

M Camici, P Zuppi, P Lorenzini, L Scarnecchia… - International Journal of …, 2021 - Elsevier
Objectives To investigate the association between sex hormones and the severity of
coronavirus disease 2019 (COVID-19). Furthermore, associations between sex hormones …

Serum level of testosterone predicts disease severity of male COVID-19 patients and is related to T-cell immune modulation by transcriptome analysis

S Zheng, Q Zou, D Zhang, F Yu, J Bao, B Lou, G Xie… - Clinica chimica acta, 2022 - Elsevier
Background Severe disease of COVID-19 and mortality occur more frequently in male
patients than that in female patients may be related to testosterone level. However, the …

High estradiol and low testosterone levels are associated with critical illness in male but not in female COVID-19 patients: a retrospective cohort study

M Schroeder, B Schaumburg, Z Mueller… - Emerging microbes & …, 2021 - Taylor & Francis
Male sex was repeatedly identified as a risk factor for death and intensive care admission.
However, it is yet unclear whether sex hormones are associated with disease severity in …

Effect of serum total testosterone and its relationship with other laboratory parameters on the prognosis of coronavirus disease 2019 (COVID-19) in SARS-CoV-2 …

S Çayan, M Uğuz, B Saylam, E Akbay - The Aging Male, 2020 - Taylor & Francis
Objective To investigate effect of serum total testosterone and its relationship with other
laboratory parameters on the prognosis of coronavirus disease 2019 (COVID-19) in severe …

Association between sex hormone levels and clinical outcomes in patients with COVID-19 admitted to hospital: an observational, retrospective, cohort study

A Beltrame, P Salguero, E Rossi, A Conesa… - Frontiers in …, 2022 - frontiersin.org
Understanding the cause of sex disparities in COVID-19 outcomes is a major challenge. We
investigate sex hormone levels and their association with outcomes in COVID-19 patients …

Role of testosterone in COVID-19 patients–A double-edged sword?

AN Hussain, F Hussain, SK Hashmi - Medical hypotheses, 2020 - Elsevier
COVID-19 affects males twice as frequently as females with significantly increased severity
and mortality. Current data suggest a direct correlation between the lower level of serum …

The relationship of serum testosterone levels with the clinical course and prognosis of COVID‐19 disease in male patients: a prospective study

AE Cinislioglu, N Cinislioglu, SO Demirdogen… - …, 2022 - Wiley Online Library
Background A potential role of testosterone among sex hormones has been hypothesized in
identifying sex‐related differences in the clinical consequences of severe acute respiratory …

Testosterone and Covid‐19: an update

A Yassin, R Shabsigh, RM Al‐Zoubi… - Reviews in Medical …, 2023 - Wiley Online Library
There is overwhelming evidence to suggest that male gender is at a higher risk of
developing more severe Covid‐19 disease and thus having poorer clinical outcomes …

Testosterone deficiency is a risk factor for severe COVID-19

L Lanser, FR Burkert, L Thommes, A Egger… - Frontiers in …, 2021 - frontiersin.org
Background Male sex is related to increased COVID-19 severity and fatality although
confirmed infections are similarly distributed between men and women. The aim of this …

Low testosterone levels predict clinical adverse outcomes in SARS‐CoV‐2 pneumonia patients

G Rastrelli, V Di Stasi, F Inglese, M Beccaria… - …, 2021 - Wiley Online Library
Background The pandemic of new severe acute respiratory syndrome (SARS) due to
coronavirus (CoV) 2 (SARS‐CoV‐2) has stressed the importance of effective diagnostic and …