The aim of this study was to improve dissolution rate of poorly water-soluble drug, cilostazol,
using supercritical antisolvent (SAS) process. The effect of process variables, such as …

The aim of this study was to improve wettability and dissolution rate of a poorly water-soluble
drug, cilostazol, using the supercritical antisolvent (SAS) process. The solid state of particles …

In pharmaceutical industry, many drugs exhibit poor solubility in biological fluid. Solubility of
drugs affects on the rate of dissolution and bioavailability in biological fluids. The …

Recrystallization and micronization for an antibacterial active pharmaceutical ingredient
(API), sulfathiazole, was investigated in this study using the supercritical antisolvent (SAS) …

Micronization of an antibiotic compound sulfamethoxazole was investigated in this study
using the supercritical anti-solvent (SAS) precipitation method. The results from either the …

The aim of this study is to improve mixing in supercritical anti-solvent process (SAS) with
impinging jets in order to form finer particles of sulfathiazole, a poorly water-soluble drug …

In this study, the rapid expansion of supercritical solution (RESS) process was used to
precipitate fine solid particles of amoxiccilin where supercritical carbon dioxide was used as …

The rapid expansion of a supercritical solution (RESS) process is an attractive technology
for the production of small, uniform and solvent-free particles of low vapour pressure solutes …

The purpose of this study was to investigate the influence of the supercritical CO 2
processing on the particle size and morphology of puerarin crystals. The process …

The particle sizes of the pharmaceutical substances are important for their bioavailability.
The bioavailability can be improved by reducing the particle size of the drug. In this study …