Micronization of cilostazol using supercritical antisolvent (SAS) process: effect of process parameters
The aim of this study was to improve dissolution rate of poorly water-soluble drug, cilostazol,
using supercritical antisolvent (SAS) process. The effect of process variables, such as …
using supercritical antisolvent (SAS) process. The effect of process variables, such as …
Enhancement of wettability and dissolution properties of cilostazol using the supercritical antisolvent process: effect of various additives
The aim of this study was to improve wettability and dissolution rate of a poorly water-soluble
drug, cilostazol, using the supercritical antisolvent (SAS) process. The solid state of particles …
drug, cilostazol, using the supercritical antisolvent (SAS) process. The solid state of particles …
Crystallization of micro particles of sulindac using rapid expansion of supercritical solution
AZ Hezave, F Esmaeilzadeh - Journal of Crystal Growth, 2010 - Elsevier
In pharmaceutical industry, many drugs exhibit poor solubility in biological fluid. Solubility of
drugs affects on the rate of dissolution and bioavailability in biological fluids. The …
drugs affects on the rate of dissolution and bioavailability in biological fluids. The …
Recrystallization and micronization of sulfathiazole by applying the supercritical antisolvent technology
YM Chen, M Tang, YP Chen - Chemical Engineering Journal, 2010 - Elsevier
Recrystallization and micronization for an antibacterial active pharmaceutical ingredient
(API), sulfathiazole, was investigated in this study using the supercritical antisolvent (SAS) …
(API), sulfathiazole, was investigated in this study using the supercritical antisolvent (SAS) …
Micronization of sulfamethoxazole using the supercritical anti-solvent process
YP Chang, M Tang, YP Chen - Journal of materials science, 2008 - Springer
Micronization of an antibiotic compound sulfamethoxazole was investigated in this study
using the supercritical anti-solvent (SAS) precipitation method. The results from either the …
using the supercritical anti-solvent (SAS) precipitation method. The results from either the …
Drug recrystallization using supercritical anti-solvent (SAS) process with impinging jets: Effect of process parameters
The aim of this study is to improve mixing in supercritical anti-solvent process (SAS) with
impinging jets in order to form finer particles of sulfathiazole, a poorly water-soluble drug …
impinging jets in order to form finer particles of sulfathiazole, a poorly water-soluble drug …
Fabrication of micron level particles of amoxicillin by rapid expansion of supercritical solution
AZ Hezave, F Esmaeilzadeh - Journal of dispersion science and …, 2012 - Taylor & Francis
In this study, the rapid expansion of supercritical solution (RESS) process was used to
precipitate fine solid particles of amoxiccilin where supercritical carbon dioxide was used as …
precipitate fine solid particles of amoxiccilin where supercritical carbon dioxide was used as …
Particle preparation of pharmaceutical compounds using supercritical antisolvent process: current status and future perspectives
The low aqueous solubility and subsequently slow dissolution rate, as well as the poor
bioavailability of several active pharmaceutical ingredients (APIs), are major challenges in …
bioavailability of several active pharmaceutical ingredients (APIs), are major challenges in …
Micronization of drug particles via RESS process
AZ Hezave, F Esmaeilzadeh - The Journal of Supercritical Fluids, 2010 - Elsevier
The rapid expansion of a supercritical solution (RESS) process is an attractive technology
for the production of small, uniform and solvent-free particles of low vapour pressure solutes …
for the production of small, uniform and solvent-free particles of low vapour pressure solutes …
[HTML][HTML] Effect of process parameters on the recrystallization and size control of puerarin using the supercritical fluid antisolvent process
Y Li, Y Yu, H Wang, F Zhao - asian journal of pharmaceutical sciences, 2016 - Elsevier
The purpose of this study was to investigate the influence of the supercritical CO 2
processing on the particle size and morphology of puerarin crystals. The process …
processing on the particle size and morphology of puerarin crystals. The process …
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- process parameters supercritical antisolvent
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- antisolvent process enhancement of wettability
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- process parameters impinging jets