pH-dependent entry of severe acute respiratory syndrome coronavirus is mediated by the spike glycoprotein and enhanced by dendritic cell transfer through DC-SIGN

ZY Yang, Y Huang, L Ganesh, K Leung… - Journal of …, 2004 - Am Soc Microbiol
The severe acute respiratory syndrome coronavirus (SARS-CoV) synthesizes several
putative viral envelope proteins, including the spike (S), membrane (M), and small envelope …

Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry

G Simmons, JD Reeves… - Proceedings of the …, 2004 - National Acad Sciences
Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is a rapidly
emerging pathogen with potentially serious consequences for public health. Here we …

Anti-severe acute respiratory syndrome coronavirus spike antibodies trigger infection of human immune cells via a pH-and cysteine protease-independent FcγR …

M Jaume, MS Yip, CY Cheung, HL Leung… - Journal of …, 2011 - Am Soc Microbiol
Public health measures successfully contained outbreaks of the severe acute respiratory
syndrome coronavirus (SARS-CoV) infection. However, the precursor of the SARS-CoV …

The M, E, and N structural proteins of the severe acute respiratory syndrome coronavirus are required for efficient assembly, trafficking, and release of virus-like …

YL Siu, KT Teoh, J Lo, CM Chan, F Kien… - Journal of …, 2008 - Am Soc Microbiol
The production of virus-like particles (VLPs) constitutes a relevant and safe model to study
molecular determinants of virion egress. The minimal requirement for the assembly of VLPs …

[HTML][HTML] Genetic analysis of the SARS-coronavirus spike glycoprotein functional domains involved in cell-surface expression and cell-to-cell fusion

CM Petit, JM Melancon, VN Chouljenko, R Colgrove… - Virology, 2005 - Elsevier
The SARS-coronavirus (SARS-CoV) is the etiological agent of severe acute respiratory
syndrome (SARS). The SARS-CoV spike (S) glycoprotein mediates membrane fusion events …

Expression of SARS-coronavirus envelope protein in Escherichia coli cells alters membrane permeability

Y Liao, J Lescar, JP Tam, DX Liu - Biochemical and biophysical research …, 2004 - Elsevier
To promote viral entry, replication, release, and spread to neighboring cells, many cytolytic
animal viruses encode proteins responsible for modification of host cell membrane …

S protein of severe acute respiratory syndrome-associated coronavirus mediates entry into hepatoma cell lines and is targeted by neutralizing antibodies in infected …

H Hofmann, K Hattermann, A Marzi… - Journal of …, 2004 - Am Soc Microbiol
The severe acute respiratory syndrome-associated coronavirus (SARS-CoV) causes severe
pneumonia with a fatal outcome in approximately 10% of patients. SARS-CoV is not closely …

Important role for the transmembrane domain of severe acute respiratory syndrome coronavirus spike protein during entry

R Broer, B Boson, W Spaan, FL Cosset… - Journal of virology, 2006 - Am Soc Microbiol
The spike protein (S) of severe acute respiratory syndrome coronavirus (SARS-CoV) is
responsible for receptor binding and membrane fusion. It contains a highly conserved …

Cellular entry of the SARS coronavirus

H Hofmann, S Pöhlmann - Trends in microbiology, 2004 - cell.com
Enveloped viruses have evolved membrane glycoproteins (GPs) that mediate entry into host
cells. These proteins are important targets for antiviral therapies and vaccines. Several …

Differential maturation and subcellular localization of severe acute respiratory syndrome coronavirus surface proteins S, M and E

B Nal, C Chan, F Kien, L Siu, J Tse… - Journal of general …, 2005 - microbiologyresearch.org
Post-translational modifications and correct subcellular localization of viral structural
proteins are prerequisites for assembly and budding of enveloped viruses. Coronaviruses …